The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Cancer System Epidemiology Insights and Future Opportunities
Systems epidemiology offers a more comprehensive and holistic approach to studies of cancer in populations by considering high dimensionality measures from multiple domains, assessing the…
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Medicine & Health Priorities for HIV service delivery: Evidence, implementation and future directions
This collection builds on the previous priority setting process to publish key evidence reviews with complimentary targeted commentaries that inform the updated 2021 guidelines. Supporting evidence…
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Medicine & Health Early Detection and Minimal Residual Disease
Future opportunities to advance patient care include those linked with the development of new technologies for early tumour detection, since patients whose cancers are detected early may have better…
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Medicine & Health Global Child Health: From Birth to Adolescence and Beyond
In 2000, the UN adopted the Millennium Development Goals (MDGs), which were intended to address key determinants of human health and welfare, including poverty, hunger, and disease. One of the MDGs…
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Biology & Life Sciences Health & Health Care in Gender Diverse Communities
The approach to health care for trans and gender diverse individuals is evolving in response to expanding knowledge of the needs in these communities, as well as a growing understanding of the…
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collection Public Health Implications of a Changing Climate
This Collection uses the lens of climate change to address effects on public health with a particular focus on the spread of infectious diseases. These articles present impactful research on One…
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Medicine & Health Trafficking, Exploitation and Health
The health consequences of human trafficking and exploitation are sufficiently prevalent and damaging that they comprise a public health problem of global magnitude. This PLOS Collection offers…
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collection Veterans Disability & Rehabilitation Research
A global forum for veteran-focused rehabilitation research…
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Medicine & Health Regulatory Harmonization Collection
While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…
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Medicine & Health Advances in Clinical Trial Design for Development of New Treatments for Tuberculosis
With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…