The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Advances in Clinical Trial Design for Development of New Treatments for TuberculosisView Collection
With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…
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Medicine & Health High-Quality Health SystemsView Collection
High quality health care will be critical to attaining the Sustainable Development Goals in low- and middle income countries. However, little is known on levels of quality and its distribution within…
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collection Refugee and Migrant HealthView Collection
At the 72nd World Health Assembly held during May 20–28 of this year in Geneva, Switzerland, a very welcome global action plan was agreed which seeks to establish a “framework of…
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collection Antimicrobial ResistanceView Collection
An increasingly pressing public health issue, antimicrobial resistance currently imposes a high burden on health care systems globally and is projected to have a significant and worsening impact in…
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collection Substance Use, Misuse, and Dependence: Prevention and TreatmentView Collection
Substance use and misuse affect people worldwide, of all ages and from all walks of life, resulting in a substantial burden of ill health and mortality, and presenting big challenges in prevention and…
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Medicine & Health PLOS Medicine’s 15th AnniversaryView Collection
In October 2019, PLOS Medicine celebrates its 15th year of publishing excellent medical research. To celebrate, the PLOS Medicine team and several editorial board members have reflected upon the last…
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Research Analysis & Policy Open AccessView Collection
In keeping with our primary mission of making the world’s scientific and medical literature a public resource, PLOS periodically publishes articles that explore the issues surrounding open…
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Medicine & Health Machine Learning in Health and BiomedicineView Collection
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…
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Medicine & Health WHO Estimates of the Global Burden of Foodborne DiseasesView Collection
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: New Mathematical Models for Prioritizing Sub-Populations by Age & GeographyView Collection
This PLOS Collection features new mathematical models that can help country decision-makers examine the potential effects of targeting sub-populations for voluntary medical male circumcision services…