The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Replication of influential studies evaluating interventions for HIV prevention and treatmentView Collection
Three decades of work on HIV prevention and treatment have yielded effective biomedical, behavioral, social, and structural interventions in controlled trials. Few of these have been adopted at a…
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Medicine & Health PLOS Medicine’s 15th AnniversaryView Collection
In October 2019, PLOS Medicine celebrates its 15th year of publishing excellent medical research. To celebrate, the PLOS Medicine team and several editorial board members have reflected upon the last…
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Biology & Life Sciences WorldLeish-6View Collection
There are currently 350 million people in 98 countries at risk of developing leishmaniasis, the vector-borne parasitic disease caused by various species of trypanosomatid protozoa in the genus of…
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Medicine & Health Challenges in Environmental Health: Closing the Gap between Evidence and RegulationsView Collection
Over 80,000 chemicals are used in commerce in the United States, and many are produced in quantities of over 1 million pounds per year. Numerous chemicals are detected in the blood and urine of nearly…
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Medicine & Health Machine Learning in Health and BiomedicineView Collection
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…
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Medicine & Health WHO Estimates of the Global Burden of Foodborne DiseasesView Collection
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and…
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Medicine & Health DREAMS: a partnership to reduce HIV acquisition among adolescent girls and young women and generate lessons for preventionView Collection
The DREAMS Partnership is a large investment by PEPFAR and private sector partners to promote empowerment and prevent HIV acquisition through a core package of interventions for young women, their…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: New Mathematical Models for Prioritizing Sub-Populations by Age & GeographyView Collection
This PLOS Collection features new mathematical models that can help country decision-makers examine the potential effects of targeting sub-populations for voluntary medical male circumcision services…
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Medicine & Health Fortification AssessmentView Collection
The Fortification Assessment Coverage Toolkit (FACT) is a modular survey methodology developed by the Global Alliance for Improved Nutrition to assess population-based (i.e., staple foods and/or…
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Medicine & Health Advances in HIV Prevention, Treatment and CureView Collection
HIV infection continues to pose a critical risk to health in many countries. UNAIDS estimates that as of 2016 the total HIV-infected population was 36.7 million, including 1.8 million people newly…