The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Research Analysis & Policy Meta-Research: Sources of Bias
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Biology & Life Sciences Editor’s Picks: Human Genetics
Human Genetics encompasses vast areas of study, including genetic epidemiology, genomics, gene therapy, epigenetics, and evolution. The very latest research in these areas and more will be on display…
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Medicine & Health Burden of Infectious Diseases in Europe
The Burden of Communicable Diseases in Europe (BCoDE) aimed to estimate the burden of communicable diseases applying a pathogen and incidence based approach to estimating DALYs (Disability Adjusted…
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Medicine & Health The Prevention, Diagnosis and Treatment of Sexually Transmitted Infections
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted infections (STIs) occur each day, incurring a very substantial burden of morbidity…
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Medicine & Health Minimally invasive autopsy for cause of death determination in high burden settings
In most middle and low-income countries, mortality data are crucial information to prioritize health policies but are inferred through highly inaccurate methods. Minimally invasive autopsy, a newly…
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Research Analysis & Policy Meta-Research: Reporting
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Research Analysis & Policy Reporting Guidelines
Reporting guidelines are statements intended to advise authors reporting research methods and findings. They can be presented as a checklist, flow diagram or text, and describe what is required to…
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Medicine & Health Disease Mongering
To mark the first academic meeting on disease mongering (the "selling of sickness" in order to promote drug sales), which was held in Newcastle, Australia in April 2006, and to help provoke…
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Medicine & Health Are Drug Companies Living Up to Their Human Rights Responsibilities? Three Viewpoints
In September 2010, the PLOS Medicine Debate asked whether drug companies are living up to their human rights responsibilities. Sofia Gruskin and Zyde Raadfrom the Harvard School of Public Health say…
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Medicine & Health Ghostwriting Collection
Ghostwriting occurs when someone has made substantial contributions to writing a manuscript but this role is unacknowledged. In medicine, ghostwriting is problematical because it often involves…