The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Burden of Infectious Diseases in Europe
The Burden of Communicable Diseases in Europe (BCoDE) aimed to estimate the burden of communicable diseases applying a pathogen and incidence based approach to estimating DALYs (Disability Adjusted…
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Medicine & Health Cardiovascular Science
The complexity of the cardiovascular system has sparked increasing interest in characterizing the interplay between different components of the heart and blood vessels. In this collection of articles…
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Biology & Life Sciences Advances in HIV Mucosal Immunology: Challenges and Opportunities
Without reliable methods to evaluate how the mucosal immune system responds to an experimental HIV vaccine, important information about how well that vaccine worked is missed. The HIV Mucosal…
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Medicine & Health The Prevention, Diagnosis and Treatment of Sexually Transmitted Infections
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted infections (STIs) occur each day, incurring a very substantial burden of morbidity…
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Medicine & Health Minimally invasive autopsy for cause of death determination in high burden settings
In most middle and low-income countries, mortality data are crucial information to prioritize health policies but are inferred through highly inaccurate methods. Minimally invasive autopsy, a newly…
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Medicine & Health Sport and Exercise Science
In this collection, PLOS ONE Associate Editor Dario Ummarino highlights some of the latest research in Sport and Exercise Science published in PLOS journals. The selection reflects the…
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Biology & Life Sciences Vectors
PLOS Neglected Tropical Diseases, the first journal dedicated to chronic and poverty-promoting infectious diseases, has long been a home for vector research. With this collection, we aim to curate the…
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Biology & Life Sciences Up For A Challenge (U4C) – Stimulating Innovation in Breast Cancer Genetic Epidemiology
Breast cancer remains a major public health problem, with more than 250,000 new cases and 40,000 deaths estimated to occur in women in the U.S. in 2017. In 2015, the National Cancer Institute (NCI…
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Biology & Life Sciences Tsetse Genome Biology
Tsetse flies are important vectors of human and animal diseases that adversely impact life in sub-Sahara Africa. A community of tsetse researchers (International Glossina Genome Initiative) have been…
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Biology & Life Sciences Visceral Leishmaniasis and HIV Co-Infection
HIV has been identified as one of the emerging challenges for visceral leishmaniasis (VL) control. HIV infection dramatically increases the risk of progression from asymptomatic infection towards…