Welcome to the Cancer Metastasis Call for Papers



Submit to PLOS ONE, the #1 publisher of cancer metastasis research. 

Deadline June 5, 2020


Guest Editors

Joe Ramos

University of hawaii

Shengyu Yang

penn state university

Helen Fillmore

University of portsmouth
united kingdom

Tobias Zech

university of liverpool
united kingdom





Scope & Topics

Cancer metastasis is responsible for 90% of all cancer deaths. The metastatic cascade is a multistep and sequential process involving cancer cell invasion, intravasation, circulation and colonization. However, our knowledge of the molecular and biochemical mechanisms that govern this process are still poorly understood. Furthermore, there is an urgent need to develop therapeutic interventions that target each part of the cascade.

In this Call for Papers, we are inviting submissions that report on the biochemical and cell biological basis of metastasis, including but not limited to cell adhesion, cell migration, cytoskeletal dynamics, cell polarity, tumour heterogeneity, tumour dormancy and the tumour microenvironment. In addition, we welcome submissions that report on disease progression and outcomes, potential biomarkers for metastatic cancer as well as the development of anti-metastatic therapies, including drug development, drug delivery and personalized medicine. In this collection, we aim to highlight the diversity of research that is being conducted in the cancer metastasis field, including studies that focus on basic and translational research.

“While great strides have been made to understand and therapeutically target the basic processes driving cancer development, immunology and growth, our understanding of the complex process of metastasis remains comparatively vague. The advent of new technologies in mechanobiology, cell adhesion, and drug development in addition to new preclinical models of cancer such as cancer organoids has initiated rapid expansion of research on metastasis. We intend for the Collection to trigger new insight and new directions in thinking about what drives metastasis and approaches to block it.”

— Dr. Joe Ramos, Guest Editor

From our Guest Editor, Helen Fillmore:

“Cancer metastasis is a complex series of processes ranging from intravasation, dissemination and extravasion, to name a few steps. Unfortunately, metastatic cancer remains the most common cause of all cancer deaths. I am excited to be a part of this project to help highlight the diversity of research across many disciplines and bring together a selection of quality reports in this area.

Research addressing basic science mechanism, identification of potential biomarkers, understanding tumor microenvironment and translational areas such as in the area of novel therapeutics are examples of the breadth of topics. This is a fascinating field with many questions including why some specific cancers are more likely to spread to specific organs. I look forward to working with PLOS ONE on this mission.”

cancer metastasis research AT PLOS ONE



DAYS to First Decision on average


cancer metastasis papers published


publisher of cancer metastasis papers


citations of PLOS ONE cancer metastasis papers

“Publishing negative data helps move science forward. Another lab shouldn't spend money and time repeating the same experiments only to come out with negative data.”
PLOS ONE author Yvonne Fondufe-Mittendorf

5+ Million

Monthly Site visitors


disciplines respresented by authors from 200 countries


Years of publishing interdisciplinary cancer metastasis


interdisciplinary cancer metastasis papers published

“It’s an amazing experience for me to publish my work with PLOS ONE. It’s a very high quality research journal with a genuine Editorial Board and reviewers, who focus on research quality.”
PLOS ONE author Maria Yousef from Pakistan
Top viewed articles 

“A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth” and more


Learn More

Subscribe to receive updates about this Collection.

Explore more cancer metastasis research.

Ready to Submit?

Mention the Cancer Metastasis Call for Papers in your cover letter. The Collection will publish Summer 2020.


Journal Information

PLOS ONE publishes primary research across all areas of science, including interdisciplinary research. Research articles are selected for scientific rigor rather than perceived impact.

Email questions to