Computer & Information Sciences

Calls for Papers for PLOS Collections

Science of Stories



PLOS Special Collections

Read more about PLOS Special Collections on the Special Collections information page

GLBIO 2017

A collection of research papers from the 12th Great Lakes Bioinformatics Conference (GLBIO) 2017, organized by the GLBIO Consortium.

PLOS Computational Biology: Methods

The Methods Section was launched in 2013 and has given computational method development a dedicated space in the journal.

PLOS Computational Biology: Topic Pages

The Topic Pages collection aims to increase the coverage of computational biology topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia

GLBIO/CCBC 2016 - Bioinformatics and Computational Biology

An important goal for the first joint Great Lakes Bioinformatics and the Canadian Computational Biology Conference was to foster long term collaborative relationships within the domain of computational approaches to biology.

Focus Feature – The Ethics of Big Data

This Focus Feature, led by Philip E. Bourne, addresses the ethical challenges that accompany the use of “big data” in biology and medicine. 

Focus Feature – Allostery: Concepts, Methods & Applications

This Focus Feature, led by Jin Liu and Ruth Nussinov, commemorates the 10th anniversary of PLOS Computational Biology and puts a spotlight on Allostery.

Macromolecular Structure and Dynamics

The latest advancements in computational treatments of macromolecules focusing upon recent computational methods investigating various aspects of the relationship between macromolecular structure, dynamics, and function

Open Source Toolkit: Hardware

This Collection gathers together research and web resources for “Open Labware” designs as part of an Open Source Toolkit.

PLOS Computational Biology 10th Anniversary

A PLOS Computational Biology "Taster" highlighting each section of the wide ranging articles published in the journal.

About My Lab

'About My Lab' was launched with the mission to share knowledge about lab organization and scientific management. Each Perspective represents an interview with a Principal Investigator, who shares his or her experience of running a lab by discussing selected topics in an informal and personal style.

Text Mining

A collection of the growing body of work in the area of Text Mining, bringing together major reviews and new research studies published in PLOS journals.


The Rosetta macromolecular modeling, prediction and design software suite is supported and used by a large community, who meet each year at RosettaCon. This series of three collections draw from research presented at RosettaCon, demonstrating exciting advances in the usability and methodology of Rosetta.

Stories from the Road: ISCB Student Council Collection

For the past 10 years the International Society for Computational Biology (ISCB) Student Council has provided events and activities to help support and encourage young budding scientists. This article series, written by past and present student council members, shares some of the trials and tribulations of the ISCB student community.

Translational Bioinformatics

'Translational Bioinformatics' is a collection of PLOS Computational Biology Education articles which reads as a "book" to be used as a reference or tutorial for a graduate level introductory course on the science of translational bioinformatics.

Proceedings of the Third International Barcode of Life Conference, Mexico City

DNA barcoding was proposed formally in 2003 as a technique for species diagnosis and identification using short standardized gene regions. Since then, it has grown from small cottage industry status to an international initiative. This Collection includes a selection of articles from the speakers in the plenary sessions at the Mexico City barcode conference.


The PLOS Computational Biology Software Section was launched in 2011 and has been steadily gathering momentum since its beginnings. Handled by our Software Editors, Software articles highlight and describe outstanding open source software of exceptional importance that has been shown to provide new biological insights.


Recognizing the need for training and education in bioinformatics and computational biology specifically targeted to biologists, PLOS Computational Biology launched its Education section in January 2006. The goals are to provide practical tutorials and background information on important computational methods.

Conference Postcards

Conference Postcards are designed to vividly recount to those not at a conference what happened at the event that was scientifically noteworthy. Each article in this Collection is devoted to a single conference and the Postcards contained in each article are selected by PLOS editors.

RECOMB Regulatory Genomics and Systems Biology 2009

In a joint venture between PLOS Computational Biology, PLOS ONE and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB Satellite onSystems Biology, held jointly at MIT, December 2-6, 2009

The DREAM systems biology challenges: a Dialogue for Reverse Engineering Assessment and Methods

This Collection contains papers representing the output of the best performing methods in the DREAM challenges, which themselves were discussed and presented at the DREAM (Dialogue for Reverse Engineering Assessment and Methods) conferences, which have been running annually since 2007.

The Roots of Bioinformatics

This collection of essays from prominent workers in the field of bioinformatics relates how selected scientific, technological, economic, and even cultural threads came to influence the development of the field we know today.

Developing Computational Biology

A series of Perspective articles from computational biologists in a variety of countries, each of whom offers their personal viewpoint on the history, current status, and future of computational biology in their region.

PLOS Computational Biology: Editors' Outlook

The PLOS Computational Biology Editors' Outlook collection provides diverse mini reviews from members of the Editorial Board on their research areas, and includes discussions of new and future developments.


The number and scope of scientific databases has soared in recent years, creating a new profession, the biocurator. These "museum catalogers of the Internet age" face a continuous struggle of making ever growing amounts of data accessible.

Bioinformatics: Starting Early

Bioinformatics is being introduced into the school curriculum earlier and earlier as the field matures. “Bioinformatics: Starting Early” is devoted to teaching bioinformatics in secondary schools.

Core Facilities

These articles aim to explain how to set up and administrate Core Facilities, and the benefits to researchers and institutions of so doing.