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Open Highlights


Open Highlights use recent PLOS Biology research articles as keystones around which to nucleate a short synthesis of up to ten related research articles from other PLOS journals and from the wider Open Access corpus. If you like Open Highlights, you might also want to check out Slice of PLOS.


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Understanding and overcoming antibiotic resistance

Given the importance of antibiotics to modern medicine, and the growing apprehension surrounding the threat of resistance, this Open Highlight looks at the cellular mechanisms of antibiotic resistance, the evolution and spread of resistance, and techniques for combating resistance.


An appetite for understanding appetite

In an effort to understand the mechanisms that drive hunger, trigger satiety, and modulate appetite, scientists often turn to invertebrate model organisms. This Open Highlight explores recent research into how animals combine information from the outside world and from within their own bodies to decide what they should eat.


Mitochondria—a billion years of cohabitation

An engulfment of a small bacterium by a larger archaeon more than a billion years ago resulted not in death, but in one of the most successful partnerships on earth. This Open Highlight explores recent research into the interaction between mitochondria and their host cells.


Evolving as a holobiont

The composition and function of microbiomes are critical for most animals and plants, leading some to suggest that hosts and their microbiomes should be considered as single ecological unit—the holobiont. This Open Highlight explores how relationships between hosts and microbes have evolved over time.


Putting placebos to the test

Medics have long recognised the curious power of the placebo. This Open Highlight explores recent research into its biological basis and the complex ethical and practical issues that surround this phenomenon.


A Swarm of Bee Research

Bees are amazing little creatures; while some of them live solitary lifestyles, many bee species form large colonies and function as a superorganism. This Open Highlight Collection examines some of the recent advances in our understanding of these fascinating insects.


Seven Glimpses into the Emotional Brain

This Open Highlight Collection examines recent research that explores the quantification and manipulation of emotions and probes the interactions between emotions and cognitive processes such as attention and memory. 


Sex Chromosomes Do it Differently

How do the sexes compensate for having different chromosome complements? This Open Highlight assesses recent insights into the complex and diverse solutions that living things have found to this problem.


In Search of Autism’s Roots

This Open Highlights Collection explores recent research investigating the neurodevelopmental origins of autism spectrum disorder and efforts to help those with associated health problems.


Wreaking Reproductive Havoc One Chemical at a Time

This Open Highlights Collection explores recent research into the adverse effects of environmental synthetic chemicals on development and reproduction.


Living Life on a Magnet

This Open Highlights collection examines recent research into the diverse ways in which living things interact with the Earth’s magnetic field and use it for orientation and navigation.


Understanding Disease Tolerance and Resilience

This Open Highlights Collection examines recent research into disease tolerance and resilience. The relationship between infection and health is extremely complex; these papers improve our understanding of infection through the use of mathematical modelling and detailed studies of parasites.


Open Highlights Image Credit: puliarfanita, flickr.com