Skip to content

PLOS is a non-profit organization on a mission to drive open science forward with measurable, meaningful change in research publishing, policy, and practice.

Building on a strong legacy of pioneering innovation, PLOS continues to be a catalyst, reimagining models to meet open science principles, removing barriers and promoting inclusion in knowledge creation and sharing, and publishing research outputs that enable everyone to learn from, reuse and build upon scientific knowledge.

We believe in a better future where science is open to all, for all.

Medicine & Health

Replication of influential studies evaluating interventions for HIV prevention and treatment

Partnered Collections, Special Issues

Three decades of work on HIV prevention and treatment have yielded effective biomedical, behavioral, social, and structural interventions in controlled trials. Few of these have been adopted at a population level to prevent HIV. The effort needed to scale up any evidence-based intervention requires the results to be carefully reviewed, understood and confirmed. The International Initiative for Impact Evaluation (3ie) funded this Collection of replication studies to address this gap. The research covers topics related to HIV and AIDS, attempts to reproduce the original findings using existing data and any available study materials.

Image Credit: NIAID, Flickr, CC BY

Prevention Replication Studies
Treatment Replication Studies
This Collection will be updated with new content! Check back soon for more featured research.
PLOS Special Collection Partner

Bill and Melinda Gates Foundation | International Initiative for Impact Evaluation (3ie)

Back to top