Focus Feature – Allostery: Concepts, Methods & Applications

This Focus Feature, led by Jin Liu and Ruth Nussinov, commemorates the 10th anniversary of PLOS Computational Biology and puts a spotlight on Allostery. The research included is a range of both new and existing work, covering diverse methods and applications in allostery. It explores allostery in key proteins, membrane-spanning receptors and soluble hub proteins, as well as methods to predict allosteric residues, communication pathways and allosteric sites. It also addresses single proteins and assemblies, NMR, simulations and network analysis, with the overall aim of helping to clarify the phenomenon of allostery and its implications.

Image Credit: Tony Hisgett, flickr