Editor’s Picks: Chemical Tools & Probes
Small molecules that allow us to observe and manipulate biological systems by targeting and binding to specific targets are powerful tools in the field of Chemical Biology. These probes can inhibit a protein’s function, interact with nucleic acids, disrupt cellular processes and pathways, as well as allow researchers to study how a biological target functions within a given system. In this Editor’s Picks, PLOS ONE Associate Editor Carla Pegoraro highlights some of the latest research on the development and uses of chemical probes, including in vivo and in vitro imaging, drug discovery, protein functions and cellular processes.
Image Credit: http://dx.doi.org/10.1371/journal.pone.0160522.g003