Biology & Life Sciences

Ebola

Published September 26, 2016 Curated Collections

In response to the 2014 Ebola outbreak in West Africa, PLOS editors curated content from across the journals, PLOS Currents and the PLOS Blogs Network into a rapidly evolving collection of research. Like all our content, these papers are freely and openly available to download, use and reuse. Incidents such as the Ebola outbreak reinforce the importance of rapid, Open Access publishing to ensure that the latest critical data and research is accessible to those who most need it without restriction.

Image Credit: CDC Global (Frederick A. Murphy)

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Latest Update
The 2014 Outbreak
Previous Outbreaks
Pathogenesis

Latest Update

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10.1371/journal.ppat.1005731

PLOS Pathogens One Health: Addressing Global Challenges at the Nexus of Human, Animal, and Environmental Health
September 15, 2016 Waithaka Mwangi, Paul de Figueiredo, Michael F. Criscitiello
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10.1371/journal.pmed.1001908

PLOS Medicine Use of Viremia to Evaluate the Baseline Case Fatality Ratio of Ebola Virus Disease and Inform Treatment Studies: A Retrospective Cohort Study
December 1, 2015 Oumar Faye, Alessio Andronico, Ousmane Faye, Henrik Salje, Pierre-Yves Boëlle, N'Faly Magassouba, Elhadj Ibrahima Bah, Lamine Koivogui, Boubacar Diallo, Alpha Amadou Diallo, Sakoba Keita, Mandy Kader Konde, Robert Fowler, Gamou Fall, Simon Cauchemez, Amadou Alpha Sall
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CDC Global (Frederick A. Murphy)

PLOS Medicine The Individualised versus the Public Health Approach to Treating Ebola
July 28, 2015 Tom H. Boyles
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10.1371/journal.pmed.1001857

PLOS Medicine Ebola Virus Disease: Experience and Decision Making for the First Patients outside of Africa
July 28, 2015 David S. Stephens, Bruce S. Ribner, Bryce D. Gartland, Nancye R. Feistritzer, Monica M. Farley, Christian P. Larsen, John T. Fox
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10.1371/journal.pmed.1001840

PLOS Medicine Maximizing the Impact of Training Initiatives for Health Professionals in Low-Income Countries: Frameworks, Challenges, and Best Practices
June 16, 2015 Corrado Cancedda, Paul E. Farmer, Vanessa Kerry, Tej Nuthulaganti, Kirstin W. Scott, Eric Goosby, Agnes Binagwaho
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10.1371/journal.pmed.1001815

PLOS Medicine Evaluating Clinical Trial Designs for Investigational Treatments of Ebola Virus Disease
April 14, 2015 Ben S. Cooper, Maciej F. Boni, Wirichada Pan-ngum, Nicholas P. J. Day, Peter W. Horby, Piero Olliaro, Trudie Lang, Nicholas J. White, Lisa J. White, John Whitehead
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CDC Global (Frederick A. Murphy)

PLOS Medicine Strengthening the Detection of and Early Response to Public Health Emergencies: Lessons from the West African Ebola Epidemic
March 24, 2015 Mark J. Siedner, Lawrence O. Gostin, Hilarie H. Cranmer, John D. Kraemer
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CDC Global (Frederick A. Murphy)

PLOS Medicine Humanitarian Access to Unapproved Interventions in Public Health Emergencies of International Concern
February 24, 2015 Jerome Amir Singh
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CDC Global (Frederick A. Murphy)

PLOS Medicine Supporting Those Who Go to Fight Ebola
January 26, 2015 Michelle M. Mello, Maria W. Merritt, Scott D. Halpern
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CDC Global (Frederick A. Murphy)

PLOS Pathogens Effectively Communicating the Uncertainties Surrounding Ebola Virus Transmission
October 29, 2015 Andy Kilianski, Nicholas G. Evans
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Amboo Who?

PLOS Pathogens The Ebola Epidemic Crystallizes the Potential of Passive Antibody Therapy for Infectious Diseases
April 23, 2015 Arturo Casadevall, Liise-anne Pirofski
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10.1371/journal.ppat.1004992

PLOS Pathogens Interdisciplinarity and Infectious Diseases: An Ebola Case Study
August 6, 2015 Vanessa O. Ezenwa, Anne-Helene Prieur-Richard, Benjamin Roche, Xavier Bailly, Pierre Becquart, Gabriel E. García-Peña, Parviez R. Hosseini, Felicia Keesing, Annapaola Rizzoli, Gerardo Suzán, Marco Vignuzzi, Marion Vittecoq, James N. Mills, Jean-François Guégan
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10.1371/journal.ppat.1005221

PLOS Pathogens Ebolavirus Evolution: Past and Present
November 12, 2015 Marc-Antoine de La Vega, Derek Stein, Gary P Kobinger
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10.1371/journal.ppat.1004731

PLOS Pathogens Ebola Virus Entry: A Curious and Complex Series of Events
April 30, 2015 Sven Moller-Tank, Wendy Maury
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10.1371/journal.ppat.1005088

PLOS Pathogens Addressing the Complications of Ebola and Other Viral Hemorrhagic Fever Infections: Using Insights from Bacterial and Fungal Sepsis
October 1, 2015 Judith Hellman
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10.1371/journal.ppat.1005016

PLOS Pathogens Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
June 26, 2015 Marnie L. Fusco, Takao Hashiguchi, Robyn Cassan, Julia E. Biggins, Charles D. Murin, Kelly L. Warfield, Sheng Li, Frederick W. Holtsberg, Sergey Shulenin, Hong Vu, Gene G. Olinger, Do H. Kim, Kevin J. Whaley, Larry Zeitlin, Andrew B. Ward, Cory Nykiforuk, M. Javad Aman, Jody Berry, Erica Ollmann Saphire
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10.1371/journal.ppat.1005263

PLOS Pathogens Interferon-γ Inhibits Ebola Virus Infection
November 12, 2015 Bethany A. Rhein, Linda S. Powers, Kai Rogers, Manu Anantpadma, Brajesh K. Singh, Yasuteru Sakurai, Thomas Bair, Catherine Miller-Hunt, Patrick Sinn, Robert A. Davey, Martha M. Monick, Wendy Maury
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10.1371/journal.ppat.1005220

PLOS Pathogens Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention
October 29, 2015 Ziying Han, Jonathan J. Madara, Andrew Herbert, Laura I. Prugar, Gordon Ruthel, Jianhong Lu, Yuliang Liu, Wenbo Liu, Xiaohong Liu, Jay E. Wrobel, Allen B. Reitz, John M. Dye, Ronald N. Harty, Bruce D. Freedman
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10.1371/journal.ppat.1005093

PLOS Pathogens The Ebola Virus: From Basic Research to a Global Health Crisis
August 13, 2015 Robert V. Stahelin
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10.1371/journal.pone.0142216

PLOS ONE Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus
November 12, 2015 Benjamin A. Pinsky, Malaya K. Sahoo, Johanna Sandlund, Marika Kleman, Medha Kulkarni, Per Grufman, Malin Nygren, Robert Kwiatkowski, Ellen Jo Baron, Fred Tenover, Blake Denison, Russell Higuchi, Reuel Van Atta, Neil Reginald Beer, Alda Celena Carrillo, Pejman Naraghi-Arani, Chad E. Mire, Charlene Ranadheera, Allen Grolla, Nina Lagerqvist, David H. Persing
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10.1371/journal.pntd.0003509

PLOS Neglected Tropical Diseases Good and Bad News about Ebola
March 12, 2015 A. Townsend Peterson
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10.1371/journal.pone.0135859

PLOS ONE Antibody Derived Peptides for Detection of Ebola Virus Glycoprotein
October 21, 2015 Luis Mario Rodríguez-Martínez, Alan Roberto Marquez-Ipiña, Felipe López-Pacheco, Roberto Pérez-Chavarría, Juan Carlos González-Vázquez, Everardo González-González, Grissel Trujillo-de Santiago, César Alejandro Ponce-Ponce de León, Yu Shrike Zhang, Mehmet Remzi Dokmeci, Ali Khademhosseini, Mario Moisés Alvarez
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10.1371/journal.pone.0140651

PLOS ONE Evaluating Subcriticality during the Ebola Epidemic in West Africa
October 20, 2015 Wayne T. A. Enanoria, Lee Worden, Fengchen Liu, Daozhou Gao, Sarah Ackley, James Scott, Michael Deiner, Ernest Mwebaze, Wui Ip, Thomas M. Lietman, Travis C. Porco
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10.1371/journal.pntd.0004083

PLOS Neglected Tropical Diseases Ebola and Its Global Research Architecture—Need for an Improvement
September 25, 2015 David Quarcoo, Dörthe Brüggmann, Doris Klingelhöfer, David A. Groneberg
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10.1371/journal.pntd.0004113

PLOS Neglected Tropical Diseases Prognostic Analysis of Patients with Ebola Virus Disease
September 23, 2015 Xin Zhang, Yihui Rong, Lijian Sun, Liming Liu, Haibin Su, Jian Zhang, Guangju Teng, Ning Du, Haoyang Chen, Yuan Fang, Wei Zhan, Alex B. J. Kanu, Sheku M. Koroma, Bo Jin, Zhe Xu, Haihan Song
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10.1371/journal.pone.0137208

PLOS ONE Social Vulnerability and Ebola Virus Disease in Rural Liberia
September 1, 2015 John A. Stanturf, Scott L. Goodrick, Melvin L. Warren, Susan Charnley, Christie M. Stegall
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10.1371/journal.pone.0129179

PLOS ONE Mass Media and the Contagion of Fear: The Case of Ebola in America
June 11, 2015 Sherry Towers, Shehzad Afzal, Gilbert Bernal, Nadya Bliss, Shala Brown, Baltazar Espinoza, Jasmine Jackson, Julia Judson-Garcia, Maryam Khan, Michael Lin, Robert Mamada, Victor M. Moreno, Fereshteh Nazari, Kamaldeen Okuneye, Mary L. Ross, Claudia Rodriguez, Jan Medlock, David Ebert, Carlos Castillo-Chavez
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10.1371/journal.pntd.0003794

PLOS Neglected Tropical Diseases Harnessing Case Isolation and Ring Vaccination to Control Ebola
May 29, 2015 Chad Wells, Dan Yamin, Martial L. Ndeffo-Mbah, Natasha Wenzel, Stephen G. Gaffney, Jeffrey P. Townsend, Lauren Ancel Meyers, Mosoka Fallah, Tolbert G. Nyenswah, Frederick L. Altice, Katherine E. Atkins, Alison P. Galvani
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10.1371/journal.pone.0135955

PLOS ONE A Multi-Site Knowledge Attitude and Practice Survey of Ebola Virus Disease in Nigeria
August 28, 2015 Garba Iliyasu, Dimie Ogoina, Akan A. Otu, Farouq M. Dayyab, Bassey Ebenso, Daniel Otokpa, Stella Rotifa, Wisdom T. Olomo, Abdulrazaq G. Habib
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CDC Global (Frederick A. Murphy)

PLOS Neglected Tropical Diseases Responsible Use of Pop Culture and Communication in the Face of Ebola Virus
August 6, 2015 Brandon Brown, Melissa Nasiruddin, Alexander Dao, Monique Halabi
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10.1371/journal.pone.0132659

PLOS ONE External Quality Assessment of Molecular Detection of Ebola Virus in China
July 15, 2015 Guojing Wang, Yu Sun, Kuo Zhang, Tingting Jia, Mingju Hao, Dong Zhang, Le Chang, Lei Zhang, Rui Zhang, Guigao Lin, Rongxue Peng, Jinming Li
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10.1371/journal.pntd.0003671

PLOS Neglected Tropical Diseases Neglected Tropical Diseases in the Ebola-Affected Countries of West Africa
June 25, 2015 Peter J. Hotez
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10.1371/journal.pntd.0003838

PLOS Neglected Tropical Diseases Acceptability and Willingness-to-Pay for a Hypothetical Ebola Virus Vaccine in Nigeria
June 15, 2015 Maduka Donatus Ughasoro, Dorothy Omono Esangbedo, Beckie Nnenna Tagbo, Ijeoma Chigozie Mejeha
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10.1371/journal.pntd.0003652

PLOS Neglected Tropical Diseases What Factors Might Have Led to the Emergence of Ebola in West Africa?
June 4, 2015 Kathleen Alexander, Claire Sanderson, Madav Marathe, Bryan Lewis, Caitlin Rivers, Jeffery Shaman, John Drake, Eric Lofgren, Virginia Dato, Marisa Eisenberg, Stephen Eubank
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10.1371/journal.pntd.0003706

PLOS Neglected Tropical Diseases Community-Centered Responses to Ebola in Urban Liberia: The View from Below
April 9, 2015 Sharon Alane Abramowitz, Kristen E. McLean, Sarah Lindley McKune, Kevin Louis Bardosh, Mosoka Fallah, Josephine Monger, Kodjo Tehoungue, Patricia A. Omidian
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10.1371/journal.pone.0118881

PLOS ONE Homologous and Heterologous Protection of Nonhuman Primates by Ebola and Sudan Virus-Like Particles
March 20, 2015 Kelly L. Warfield, John M. Dye, Jay B. Wells, Robert C. Unfer, Frederick W. Holtsberg, Sergey Shulenin, Hong Vu, Dana L. Swenson, Sina Bavari, M. Javad Aman
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10.1371/journal.pone.0118434

PLOS ONE Mechanisms of Immunity in Post-Exposure Vaccination against Ebola Virus Infection
March 18, 2015 Steven B. Bradfute, Scott M. Anthony, Kelly S. Stuthman, Natarajan Ayithan, Prafullakumar Tailor, Carl I. Shaia, Mike Bray, Keiko Ozato, Sina Bavari
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10.1371/journal.pone.0120013

PLOS ONE A Survey of UK Healthcare Workers’ Attitudes on Volunteering to Help with the Ebola Outbreak in West Africa
March 11, 2015 Lance Turtle, Fiona McGill, Judy Bettridge, Claire Matata, Rob Christley, Tom Solomon
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10.1371/journal.pone.0142751

PLOS ONE Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays
November 12, 2015 Giada Mattiuzzo, James Ashall, Kathryn S. Doris, Kirsty MacLellan-Gibson, Carolyn Nicolson, Dianna E. Wilkinson, Ruth Harvey, Neil Almond, Robert Anderson, Stacey Efstathiou, Philip D. Minor, Mark Page
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10.1371/journal.pone.0131398

PLOS ONE Transmission Dynamics and Final Epidemic Size of Ebola Virus Disease Outbreaks with Varying Interventions
July 21, 2015 Maria Vittoria Barbarossa, Attila Dénes, Gábor Kiss, Yukihiko Nakata, Zsolt Vizi, Gergely Röst
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10.1371/journal.pone.0131000

PLOS ONE Innovative Technological Approach to Ebola Virus Disease Outbreak Response in Nigeria Using the Open Data Kit and Form Hub Technology
June 26, 2015 Daniel Tom-Aba, Adeniyi Olaleye, Adebola Tolulope Olayinka, Patrick Nguku, Ndadilnasiya Waziri, Peter Adewuyi, Olawunmi Adeoye, Saliu Oladele, Aderonke Adeseye, Olukayode Oguntimehin, Faisal Shuaib
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10.1371/journal.pone.0129333

PLOS ONE Ebola Virus Disease Outbreak in Isiro, Democratic Republic of the Congo, 2012: Signs and Symptoms, Management and Outcomes
June 24, 2015 Thomas Kratz, Paul Roddy, Antoine Tshomba Oloma, Benjamin Jeffs, Diana Pou Ciruelo, Olimpia de la Rosa, Matthias Borchert
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10.1371/journal.pntd.0003734

PLOS Neglected Tropical Diseases The Case for Improved Diagnostic Tools to Control Ebola Virus Disease in West Africa and How to Get There
June 11, 2015 Arlene C. Chua, Jane Cunningham, Francis Moussy, Mark D. Perkins, Pierre Formenty
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10.1371/journal.pntd.0003833

PLOS Neglected Tropical Diseases Risk Factors Associated with Ebola and Marburg Viruses Seroprevalence in Blood Donors in the Republic of Congo
June 5, 2015 Nanikaly Moyen, Laurence Thirion, Petra Emmerich, Amelia Dzia-Lepfoundzou, Hervé Richet, Yannik Boehmann, Yannick Dimi, Pierre Gallian, Ernest A. Gould, Stephan Günther, Xavier de Lamballerie
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10.1371/journal.pntd.0003567

PLOS Neglected Tropical Diseases Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and Some Implications for Containment
April 17, 2015 Paul Richards, Joseph Amara, Mariane C Ferme, Prince Kamara, Esther Mokuwa, Amara Idara Sheriff, Roland Suluku, Maarten Voors
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10.1371/journal.pone.0118345

PLOS ONE Virus-Like Particles Activate Type I Interferon Pathways to Facilitate Post-Exposure Protection against Ebola Virus Infection
February 26, 2015 Natarajan Ayithan, Steven B. Bradfute, Scott M. Anthony, Kelly S. Stuthman, Sina Bavari, Mike Bray, Keiko Ozato
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10.1371/journal.pone.0140810

PLOS ONE Temporal Course of 2014 Ebola Virus Disease (EVD) Outbreak in West Africa Elucidated through Morbidity and Mortality Data: A Tale of Three Countries
November 11, 2015 Ying-Hen Hsieh

The 2014 Outbreak

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Farrah Kashfipour

Speaking of Medicine How a Tree Helped a Village with Ebola Control
January 28, 2015 Farrah Kashfipour
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Eneas De Troya, Flickr

Speaking of Medicine How Will the Ebola Epidemic End?
January 27, 2015 Tom Boyles
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Chowell et al

PLOS Currents Outbreaks Is West Africa Approaching a Catastrophic Phase or is the 2014 Ebola Epidemic Slowing Down? Different Models Yield Different Answers for Liberia
November 20, 2014 Gerardo Chowell, Lone Simonsen, Cécile Viboud, Yang Kuang
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Maria A. Kiskowski

PLOS Currents Outbreaks A Three-Scale Network Model for the Early Growth Dynamics of 2014 West Africa Ebola Epidemic
November 13, 2014 Maria A. Kiskowski
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10.1371/journal.pntd.0003652

PLOS Neglected Tropical Diseases What Factors Might Have Led to the Emergence of Ebola in West Africa?
June 4, 2015 Kathleen Alexander, Claire Sanderson, Madav Marathe, Bryan Lewis, Caitlin Rivers, Jeffery Shaman, John Drake, Eric Lofgren, Virginia Dato, Marisa Eisenberg, Stephen Eubank
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Haeussler et al

PLOS Currents Outbreaks The UCSC Ebola Genome Portal
November 7, 2014 Maximilian Haeussler, Donna Karolchik, Hiram Clawson, Brian J Raney, Kate R. Rosenbloom, Pauline A. Fujita, Angie S. Hinrichs, Matthew L Speir, Chris Eisenhart, Ann S. Zweig, David Haussler, W. James Kent
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Ponomarenko et al

PLOS Currents Outbreaks Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks
November 3, 2014 Julia Ponomarenko, Kerrie Vaughan, Alessandro Sette, Sebastian Maurer-Stroh
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10.1371/journal.pntd.0003567

PLOS Neglected Tropical Diseases Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and Some Implications for Containment
April 17, 2015 Paul Richards, Joseph Amara, Mariane C Ferme, Prince Kamara, Esther Mokuwa, Amara Idara Sheriff, Roland Suluku, Maarten Voors
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DFID, Flickr

Speaking of Medicine Ebola has Taught us a Crucial Lesson about our Views of “Irrational” Health Behaviors
October 21, 2014 Sara Gorman
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Rivers et al

PLOS Currents Outbreaks Modeling the Impact of Interventions on an Epidemic of Ebola in Sierra Leone and Liberia
October 16, 2014 Caitlin M. Rivers, Eric T. Lofgren, Madhav Marathe, Stephen Eubank, Bryan L. Lewis
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Haas et al

PLOS Currents Outbreaks On the Quarantine Period for Ebola Virus
October 14, 2014 Charles N. Haas
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Stadler et al

PLOS Currents Outbreaks Insights into the Early Epidemic Spread of Ebola in Sierra Leone Provided by Viral Sequence Data
October 6, 2014 Tanja Stadler, Denise Kühnert, David A. Rasmussen, Louis du Plessis
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Wesolowski et al

PLOS Currents Outbreaks Commentary: Containing the Ebola Outbreak – the Potential and Challenge of Mobile Network Data
September 29, 2014 Amy Wesolowski, Caroline O. Buckee, Linus Bengtsson, Erik Wetter, Xin Lu, Andrew J. Tatem
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Towers et al

PLOS Currents Outbreaks Temporal Variations in the Effective Reproduction Number of the 2014 West Africa Ebola Outbreak
September 18, 2014 Sherry Towers, Oscar Patterson-Lomba, Carlos Castillo-Chavez
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MSF

Speaking of Medicine Ebola: a Blind Outbreak
September 18, 2014 Grazia Caleo
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Fisman et al

PLOS Currents Outbreaks Early Epidemic Dynamics of the West African 2014 Ebola Outbreak: Estimates Derived with a Simple Two-Parameter Model
September 8, 2014 David Fisman, Edwin Khoo, Ashleigh Tuite
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Gomes et al

PLOS Currents Outbreaks Assessing the International Spreading Risk Associated with the 2014 West African Ebola Outbreak
September 2, 2014 Marcelo F. C. Gomes, Ana Pastore y Piontti, Luca Rossi, Dennis Chao, Ira Longini, M. Elizabeth Halloran, Alessandro Vespignani
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Althaus

PLOS Currents Outbreaks Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa
September 2, 2014 Christian L. Althaus
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CDC

Speaking of Medicine The Global Response to the Ebola Fever Epidemic: What Took So Long?
August 22, 2014 Mark J. Siedner,John D. Kraemer
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CDC

Speaking of Medicine Ebola: Liberians Destined for Extinction
August 21, 2014 Gondah Lekpeh
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10.1371/journal.pntd.0003056

PLOS Neglected Tropical Diseases Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy
July 31, 2014 Daniel Bausch, Lara Schwarz
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Calvignac-Spencer et al

PLOS Currents Outbreaks Clock Rooting Further Demonstrates that Guinea 2014 EBOV is a Member of the Zaïre Lineage
June 16, 2014 Sébastien Calvignac-Spencer, Jakob M. Schulze, Franziska Zickmann, Bernhard Y. Renard
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Dudas et al

PLOS Currents Outbreaks Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak
May 2, 2014 Gytis Dudas, Andrew Rambaut

Previous Outbreaks

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10.1371/journal.pone.0100333

PLOS ONE Ebola Outbreak Response; Experience and Development of Screening Tools for Viral Haemorrhagic Fever (VHF) in a HIV Center of Excellence Near to VHF Epicentres
July 9, 2014 Rosalind Parkes-Ratanshi, Ali Elbireer, Betty Mbambu, Faridah Mayamja, Alex Coutinho, Concepta Merry
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10.1371/journal.pntd.0002435

PLOS Neglected Tropical Diseases Hospital-Based Surveillance for Viral Hemorrhagic Fevers and Hepatitides in Ghana
September 19, 2013 Joseph Bonney, Mubarak Osei-Kwasi, Theophilus Adiku, Jacob Barnor, Robert Amesiya, Chrysantus Kubio, Lawson Ahadzie, Stephan Ölschläger, Michaela Lelke, Beate Becker-Ziaja, Meike Pahlmann, Stephan Günther
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10.1371/journal.pone.0052986

PLOS ONE Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever Caused by a Newly Identified Virus Strain, Bundibugyo, Uganda, 2007–2008
December 28, 2012 Paul Roddy, Natasha Howard, Maria Van Kerkhove, Julius Lutwama, Joseph Wamala, Zabulon Yoti, Robert Colebunders, Pedro Pablo Palma, Esther Sterk, Benjamin Jeffs, Michel Van Herp, Matthias Borchert
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10.1371/journal.pntd.0001546

PLOS Neglected Tropical Diseases Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
June 26, 2012 Adam MacNeil, Pierre Rollin
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10.1371/journal.ppat.1000212

PLOS Pathogens Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
November 21, 2008 Jonathan S. Towner, Tara K. Sealy, Marina L. Khristova, César G. Albariño, Sean Conlan, Serena A. Reeder, Phenix-Lan Quan, W. Ian Lipkin, Robert Downing, Jordan W. Tappero, Samuel Okware, Julius Lutwama, Barnabas Bakamutumaho, John Kayiwa, James A. Comer, Pierre E. Rollin, Thomas G. Ksiazek, Stuart T. Nichol
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10.1371/journal.ppat.0030002

PLOS Pathogens Effective Post-Exposure Treatment of Ebola Infection
January 19, 2007 Heinz Feldmann, Steven M Jones, Kathleen M Daddario-DiCaprio, Joan B Geisbert, Ute Ströher, Allen Grolla, Mike Bray, Elizabeth A Fritz, Lisa Fernando, Friederike Feldmann, Lisa E Hensley, Thomas W Geisbert
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10.1371/journal.pmed.0030177

PLOS Medicine Immune Protection of Nonhuman Primates against Ebola Virus with Single Low-Dose Adenovirus Vectors Encoding Modified GPs
May 16, 2006 Nancy J Sullivan, Thomas W Geisbert, Joan B Geisbert, Devon J Shedlock, Ling Xu, Laurie Lamoreaux, Jerome H. H. V Custers, Paul M Popernack, Zhi-Yong Yang, Maria G Pau, Mario Roederer, Richard A Koup, Jaap Goudsmit, Peter B Jahrling, Gary J Nabel
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10.1371/journal.pbio.0030371

PLOS Biology Wave-Like Spread of Ebola Zaire
October 25, 2005 Peter D Walsh, Roman Biek, Leslie A Real
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10.1371/journal.pmed.0010059

PLOS Medicine Containing the Threat—Don’t Forget Ebola
December 28, 2004 Jonathan Cohen

Pathogenesis

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10.1371/journal.ppat.1000904

PLOS Pathogens Demonstration of Cross-Protective Vaccine Immunity against an Emerging Pathogenic Ebolavirus Species
May 20, 2010 Lisa E. Hensley, Sabue Mulangu, Clement Asiedu, Joshua Johnson, Anna N. Honko, Daphne Stanley, Giulia Fabozzi, Stuart T. Nichol, Thomas G. Ksiazek, Pierre E. Rollin, Victoria Wahl-Jensen, Michael Bailey, Peter B. Jahrling, Mario Roederer, Richard A. Koup, Nancy J. Sullivan
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10.1371/journal.ppat.1001098

PLOS Pathogens Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein
September 9, 2010 Joseph R. Francica, Angel Varela-Rohena, Andrew Medvec, Gabriela Plesa, James L. Riley, Paul Bates
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10.1371/journal.ppat.1001110

PLOS Pathogens Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes
September 16, 2010 Mohammad F. Saeed, Andrey A. Kolokoltsov, Thomas Albrecht, Robert A. Davey
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10.1371/journal.ppat.1001121

PLOS Pathogens Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner
September 23, 2010 Asuka Nanbo, Masaki Imai, Shinji Watanabe, Takeshi Noda, Kei Takahashi, Gabriele Neumann, Peter Halfmann, Yoshihiro Kawaoka
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10.1371/journal.pntd.0001175

PLOS Neglected Tropical Diseases Serologic Cross-Reactivity of Human IgM and IgG Antibodies to Five Species of Ebola Virus
June 7, 2011 Adam MacNeil, Zachary Reed, Pierre Rollin
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10.1371/journal.pntd.0001275

PLOS Neglected Tropical Diseases A Replicating Cytomegalovirus-Based Vaccine Encoding a Single Ebola Virus Nucleoprotein CTL Epitope Confers Protection against Ebola Virus
August 9, 2011 Yoshimi Tsuda, Patrizia Caposio, Christopher Parkins, Sara Botto, Ilhem Messaoudi, Luka Cicin-Sain, Heinz Feldmann, Michael Jarvis
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10.1371/journal.pntd.0001359

PLOS Neglected Tropical Diseases Ebola Virion Attachment and Entry into Human Macrophages Profoundly Effects Early Cellular Gene Expression
October 18, 2011 Victoria Wahl-Jensen, Sabine Kurz, Friedericke Feldmann, Lukas Buehler, Jason Kindrachuk, Victor DeFilippis, Jean da Silva Correia, Klaus Früh, Jens Kuhn, Dennis Burton, Heinz Feldmann
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10.1371/journal.pone.0029608

PLOS ONE The Organisation of Ebola Virus Reveals a Capacity for Extensive, Modular Polyploidy
January 11, 2012 Daniel Beniac, Pasquale Melito, Shauna deVarennes, Shannon Hiebert, Melissa Rabb, Lindsey Lamboo, Steven Jones, Tim Booth
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10.1371/journal.ppat.1002847

PLOS Pathogens The Ebola Virus Glycoprotein Contributes to but Is Not Sufficient for Virulence In Vivo
August 2, 2012 Allison Groseth, Andrea Marzi, Thomas Hoenen, Astrid Herwig, Don Gardner, Stephan Becker, Hideki Ebihara, Heinz Feldmann
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10.1371/journal.ppat.1003065

PLOS Pathogens Antigenic Subversion: A Novel Mechanism of Host Immune Evasion by Ebola Virus
December 13, 2012 Gopi Mohan, Wenfang Li, Ling Ye, Richard Compans, Chinglai Yang
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10.1371/journal.pone.0061232

PLOS ONE Ebolavirus Nucleoprotein C-Termini Potently Attract Single Domain Antibodies Enabling Monoclonal Affinity Reagent Sandwich Assay (MARSA) Formulation
April 5, 2013 Laura Sherwood, Andrew Hayhurst
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10.1371/journal.pone.0060579

PLOS ONE A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
April 5, 2013 Peter Madrid, Sidharth Chopra, Ian Manger, Lynne Gilfillan, Tiffany Keepers, Amy Shurtleff, Carol Green, Lalitha Iyer, Holli Dilks, Robert Davey, Andrey Kolokoltsov, Ricardo Carrion Jr., Jean Patterson, Sina Bavari, Rekha Panchal, Travis Warren, Jay Wells, Walter Moos, RaeLyn Burke, Mary Tanga
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10.1371/journal.ppat.1003389

PLOS Pathogens Antibody Quality and Protection from Lethal Ebola Virus Challenge in Nonhuman Primates Immunized with Rabies Virus Based Bivalent Vaccine
May 30, 2013 Joseph E. Blaney Blaney, Andrea Marzi, Mallory Willet, Amy Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, Matthias Schnell
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10.1371/journal.pntd.0002430

PLOS Neglected Tropical Diseases A Fusion-Inhibiting Peptide against Rift Valley Fever Virus Inhibits Multiple, Diverse Viruses
September 12, 2013 Jeffrey Koehler, Jeffrey Smith, Daniel Ripoll, Kristin Spik, Shannon Taylor, Catherine Badger, Rebecca Grant, Monica Ogg, Anders Wallqvist, Mary Guttieri, Robert Garry, Connie Schmaljohn
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10.1371/journal.ppat.1003677

PLOS Pathogens Ebola Virus RNA Editing Depends on the Primary Editing Site Sequence and an Upstream Secondary Structure
October 17, 2013 Masfique Mehedi, Thomas Hoenen, Shelly Robertson, Stacy Ricklefs, Michael Dolan, Travis Taylor, Darryl Falzarano, Hideki Ebihara, Stephen Porcella, Heinz Feldmann
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10.1371/journal.pone.0089735

PLOS ONE Toll-Like Receptor Agonist Augments Virus-Like Particle-Mediated Protection from Ebola Virus with Transient Immune Activation
February 24, 2014 Karen Martins, Jesse Steffens, Sean van Tongeren, Jay Wells, Alison Bergeron, Samuel Dickson, John Dye, Andres Salazar, Sina Bavari
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10.1371/journal.pone.0096360

PLOS ONE Identification of Continuous Human B-Cell Epitopes in the VP35, VP40, Nucleoprotein and Glycoprotein of Ebola Virus
June 10, 2014 Pierre Becquart, Tanel Mahlakõiv, Dieudonné Nkoghe, Eric Leroy
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10.1371/journal.pntd.0003061

PLOS Neglected Tropical Diseases Transcriptional Correlates of Disease Outcome in Anticoagulant-Treated Non-Human Primates Infected with Ebolavirus
July 31, 2014 Sara Garamszegi, Judy Yen, Anna Honko, Joan Geisbert, Kathleen Rubins, Thomas Geisbert, Yu Xia, Lisa Hensley, John Connor
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10.1371/journal.pntd.0003095

PLOS Neglected Tropical Diseases High Content Image-Based Screening of a Protease Inhibitor Library Reveals Compounds Broadly Active against Rift Valley Fever Virus and Other Highly Pathogenic RNA Viruses
August 21, 2014 Rajini Mudhasani, Krishna Kota, Cary Retterer, Julie Tran, Chris Whitehouse, Sina Bavari
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10.1371/journal.ppat.1004509

PLOS Pathogens Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability
November 20, 2014 Beatriz Escudero-Pérez, Valentina Volchkova, Olga Dolnik, Philip Lawrence, Viktor Volchkov