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Biology & Life Sciences

The many facets of immunometabolism

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Since immunometabolism was first defined in the literature in 2011, this research area has illuminated the importance of metabolic regulation of immune function and how the regulation of metabolism by the immune system impacts human health. In recent years, the influence of immunometabolism as an upstream regulator, not just a downstream consequence of aging, infection and disease, has emphasized the importance and opportunities of this field for human health.

This collection of articles aims to shine a light on the many facets of immunometabolism, highlighting how molecular and cellular mechanisms impact diverse tissue and organismal functions and the exciting potential for leveraging immunometabolism for therapeutic interventions. Articles cover topics including the role of immunometabolites in bacterial infections, how immunometabolism affects obesity and targeting immunometabolism therapeutically.

Image Credit: NIH3T3 cell by Shogo Suga and Koki Nakamura CC BY 4.0

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