Novel infectious diseases continue to emerge within human populations. Predictive studies have begun to identify pathogen traits…
Infectious Disease Epidemiology
The threat of emerging zoonoses to public health underscores the need to assess and share research on transmission patterns and infection dynamics openly, in real time. Modern infectious disease epidemiology thus sits at an intersection of public health, disease modeling, bench science, and policy. This Collection highlights research on these many interconnected facets of infectious disease epidemiology, including emerging zoonoses, viral genomics, infection dynamics, and disease surveillance and modeling.
Submit your research to PLOS ONE, PLOS Biology, PLOS Medicine, PLOS Genetics, PLOS Global Public Health, PLOS Computational Biology, PLOS Pathogens, PLOS Neglected Tropical Diseases or PLOS Water to feature your research in this collection.
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PLOS Biology Tissue tropism and transmission ecology predict virulence of human RNA viruses
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PLOS Biology Combining genomics and epidemiology to track mumps virus transmission in the United States
Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and…
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PLOS Biology Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This…
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PLOS Biology “Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence
The mechanisms underlying virus emergence are rarely well understood, making the appearance of outbreaks largely unpredictable. Bluetongue…
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PLOS Biology Real-time public health communication of local SARS-CoV-2 genomic epidemiology
Genomic epidemiology can provide a unique, real-time understanding of SARS-CoV-2 transmission patterns. Yet the potential for genomic…
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PLOS Biology Optimising risk-based surveillance for early detection of invasive plant pathogens
Emerging infectious diseases (EIDs) of plants continue to devastate ecosystems and livelihoods worldwide. Effective management requires…
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PLOS Biology Superspreading events in the transmission dynamics of SARS-CoV-2: Opportunities for interventions and control
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of the Coronavirus Disease 2019 (COVID-19) disease,…
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PLOS Biology Monitor for COVID-19 vaccine resistance evolution during clinical trials
Although less common than the evolution of antimicrobial drug resistance, vaccine resistance can and has evolved. How likely is it that…
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PLOS Biology Patterns of smallpox mortality in London, England, over three centuries
Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control…
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PLOS Biology Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis
Bacillus anthracis, a spore-forming gram-positive bacterium, causes anthrax. The external surface of the exosporium is coated with…
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PLOS Neglected Tropical Diseases The use of serology for trachoma surveillance: Current status and priorities for future investigation
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PLoS Neglected Tropical Diseases Identifying the outbreak signal of COVID-19 before the response of the traditional disease monitoring system
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PLOS Computational Biology Real-time estimation of disease activity in emerging outbreaks using internet search information
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PLOS Neglected Tropical Diseases Epidemiology of dengue fever in Guatemala
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PLOS Neglected Tropical Diseases The COVID-19 pandemic should not derail global vector control efforts
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PLOS Neglected Tropical Diseases Acute Chagas disease in Brazil from 2001 to 2018: A nationwide spatiotemporal analysis
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PLOS Computational Biology Socioeconomic bias in influenza surveillance
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PLOS Computational Biology Calibration of individual-based models to epidemiological data: A systematic review
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PLOS Neglected Tropical Diseases Post-elimination surveillance in formerly onchocerciasis endemic focus in Southern Mexico
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PLOS Neglected Tropical Diseases The Galabat-Metema cross-border onchocerciasis focus: The first coordinated interruption of onchocerciasis transmission in Africa
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PLOS Neglected Tropical Diseases Epidemiology of Congenital Rubella Syndrome (CRS) in India, 2016-18, based on data from sentinel surveillance
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PLOS Computational Biology Accuracy of real-time multi-model ensemble forecasts for seasonal influenza in the U.S.
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PLOS Computational Biology Efficient sentinel surveillance strategies for preventing epidemics on networks
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PLOS Neglected Tropical Diseases Development and Validation of a simple score for diagnosis of Leptospirosis at outpatient departments
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PLOS Neglected Tropical Diseases Cutaneous leishmaniasis in Syria: A review of available data during the war years: 2011–2018
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PLOS Neglected Tropical Diseases Global knowledge gaps in acute febrile illness etiologic investigations: A scoping review
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PLOS Computational Biology Seasonal influenza: Modelling approaches to capture immunity propagation
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PLOS Neglected Tropical Diseases Village-scale persistence and elimination of gambiense human African trypanosomiasis
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PLOS Neglected Tropical Diseases A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy
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PLOS Neglected Tropical Diseases Intrinsic and extrinsic drivers of transmission dynamics of hemorrhagic fever with renal syndrome caused by Seoul hantavirus
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PLOS Neglected Tropical Diseases Detecting space-time clusters of dengue fever in Panama after adjusting for vector surveillance data
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PLOS Neglected Tropical Diseases Prevalence and environmental determinants of cutaneous leishmaniasis in rural communities in Tigray, northern Ethiopia
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PLOS Neglected Tropical Diseases Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s
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PLOS Neglected Tropical Diseases EDITOR’S PICK – The seasonality of diarrheal pathogens: A retrospective study of seven sites over three years
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PLOS Computational Biology Long-term dynamics of measles in London: Titrating the impact of wars, the 1918 pandemic, and vaccination
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PLOS Neglected Tropical Diseases Endemic Disease Control Agents’ perception on the fight against Aedes aegypti and the prevention of arbovirus infections in Brazil
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PLOS Neglected Tropical Diseases Chikungunya-attributable deaths: A neglected outcome of a neglected disease
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PLOS Computational Biology Reappraising the utility of Google Flu Trends
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PLOS Neglected Tropical Diseases Entomological assessment of dengue virus transmission risk in three urban areas of Kenya
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PLOS Neglected Tropical Diseases An evaluation of Brazil’s surveillance and prophylaxis of canine rabies between 2008 and 2017
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PLOS Neglected Tropical Diseases Large scale detailed mapping of dengue vector breeding sites using street view images
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PLOS Neglected Tropical Diseases Estimating undetected Ebola spillovers
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PLOS Neglected Tropical Diseases Prioritizing surveillance of Nipah virus in India
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PLOS Neglected Tropical Diseases Cholera prevention and control in refugee settings: Successes and continued challenges
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PLOS Neglected Tropical Diseases Assessing dengue control in Tokyo, 2014
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PLOS Neglected Tropical Diseases Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi
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PLOS Neglected Tropical Diseases The characteristics of current natural foci of hemorrhagic fever with renal syndrome in Shandong Province, China, 2012-2015
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PLOS Neglected Tropical Diseases Preexisting chronic conditions for fatal outcome among SFTS patients: An observational Cohort Study
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PLOS Neglected Tropical Diseases El Niño Southern Oscillation, overseas arrivals and imported chikungunya cases in Australia: A time series analysis
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PLOS Neglected Tropical Diseases Potential animal reservoirs (dogs and bats) of human visceral leishmaniasis due to Leishmania infantum in French Guiana
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PLOS Neglected Tropical Diseases Towards harmonisation of entomological surveillance in the Mediterranean area
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PLOS Neglected Tropical Diseases Unbiased assessment of disease surveillance utilities: A prospect theory application
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PLOS Computational Biology The statistics of epidemic transitions
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PLOS Neglected Tropical Diseases Dengue infection in India: A systematic review and meta-analysis
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PLOS Computational Biology Nonmechanistic forecasts of seasonal influenza with iterative one-week-ahead distributions
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PLOS Neglected Tropical Diseases A real-time medical cartography of epidemic disease (Nodding syndrome) using village-based lay mHealth reporters
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PLOS Neglected Tropical Diseases Molecular characterization of Vibrio cholerae responsible for cholera epidemics in Uganda by PCR, MLVA and WGS
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PLOS Neglected Tropical Diseases Enhanced surveillance for Rift Valley Fever in livestock during El Niño rains and threat of RVF outbreak, Kenya, 2015-2016
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PLOS Neglected Tropical Diseases Zika virus infection and microcephaly: Evidence regarding geospatial associations
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PLOS Computational Biology Need for speed: An optimized gridding approach for spatially explicit disease simulations
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PLOS Neglected Tropical Diseases Geospatial-temporal distribution of Tegumentary Leishmaniasis in Colombia (2007–2016)
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PLOS Neglected Tropical Diseases Rabies in the Americas: 1998-2014
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PLOS Neglected Tropical Diseases The seasonal influence of climate and environment on yellow fever transmission across Africa
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PLOS Neglected Tropical Diseases Spatio-temporal coherence of dengue, chikungunya and Zika outbreaks in Merida, Mexico
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PLOS Computational Biology Deploying digital health data to optimize influenza surveillance at national and local scales
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PLOS Neglected Tropical Diseases Changing demographics of visceral leishmaniasis in northeast Brazil: Lessons for the future
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PLOS Computational Biology Prediction of infectious disease epidemics via weighted density ensembles
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PLOS Neglected Tropical Diseases Improved tools and strategies for the prevention and control of arboviral diseases: A research-to-policy forum
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PLOS Neglected Tropical Diseases Madagascar can build stronger health systems to fight plague and prevent the next epidemic
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PLOS Computational Biology Ten simple rules for biologists learning to program
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PLOS Neglected Tropical Diseases Identifying cholera “hotspots” in Uganda: An analysis of cholera surveillance data from 2011 to 2016
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PLOS Computational Biology MAGPIE: Simplifying access and execution of computational models in the life sciences
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PLOS Neglected Tropical Diseases Internet-based biosurveillance methods for vector-borne diseases: Are they novel public health tools or just novelties?
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PLOS Computational Biology The use of ambient humidity conditions to improve influenza forecast
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PLOS Computational Biology Individual versus superensemble forecasts of seasonal influenza outbreaks in the United States
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PLOS Computational Biology Seasonality in risk of pandemic influenza emergence
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PLOS Neglected Tropical Diseases Epidemiological consequences of immune sensitisation by pre-exposure to vector saliva
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PLOS Cholera Channel
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PLOS Tuberculosis Channel