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Mycetoma is a serious and debilitating condition that meets all of the criteria we ordinarily attribute to a neglected tropical disease (NTD). Classically, it is a destructive fungal or bacterial infection of the foot (although other body parts can be affected) that results in disfigurement and social stigma. It overwhelmingly occurs in impoverished areas of a “mycetoma belt” that extends across the globe, roughly between the Equator and the Tropic of Cancer, with most of the cases reported from India, Mexico, Sudan, several countries in Africa’s Sahel (including Chad, Mali, and Mauritania), and Somalia and Yemen.

Image Credit: Uncalno Tekno

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    Fig. 1. Prevalence and Reported Cases of Mycetoma. A: Average prevalence of mycetoma cases as calculated by the number of cases reported in a year in a certain country divided trough the total population of that country of that same year as reported by B: The average number of mycetoma cases reported per year per country. From van de Sande WWJ (2013) Global Burden of Human Mycetoma: A Systematic Review and Meta-analysis. PLoS Negl Trop Dis 7(11): e2550. doi:10.1371/journal.pntd.0002550
    Mycetoma: The PLOS NTDs Collection
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