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Pearls: Bacteria

Published July 18, 2019 Curated Collections

PLOS Pathogens presents an Open Access compendium of the "lessons-that-last." This section, founded by Dr. Hiten Madhani and now led by Dr. Joseph Heitman and a team of twelve Pearls Editors, is a living collection of short educational and highly useful articles that address topics of relevance and importance within the wide-ranging field of pathogens research, with insights for trainees and scientists at all career stages.

Image Credit: Amboo Whoo Flickr.com

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10.1371/journal.ppat.1007815

PLOS Pathogens Amino acid–derived quorum sensing molecules controlling the virulence of vibrios (and beyond)
July 11, 2019 Tom Defoirdt
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10.1371/journal.ppat.1007726

PLOS Pathogens Heteroresistance: A cause of unexplained antibiotic treatment failure?
June 6, 2019 Victor I. Band, David S. Weiss
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10.1371/journal.ppat.1007600

PLOS Pathogens Did new transmission cycles in anthropogenic, dense, host populations encourage the emergence and speciation of pathogenic Bordetella?
March 28, 2019 Kalyan K. Dewan, Eric T. Harvill
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10.1371/journal.ppat.1007529

PLOS Pathogens Cyclic diguanylate riboswitches control bacterial pathogenesis mechanisms
February 7, 2019 Rita Tamayo
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Amboo whoo? Flickr.com, 2008

PLOS Pathogens Barrett’s esophagus and esophageal cancer: Links to microbes and the microbiome
December 20, 2018 Teminioluwa Ajayi, Sarah Cantrell, Ashley Spann, Katherine Garman
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10.1371/journal.ppat.1007380

PLOS Pathogens Principles of intracellular bacterial pathogen spread from cell to cell
December 13, 2018 Erin Weddle, Hervé Agaisse
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Martinez ME (2018)

PLOS Pathogens The calendar of epidemics: Seasonal cycles of infectious diseases
November 8, 2018 Micaela Elvira Martinez
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10.1371/journal.ppat.1007310

PLOS Pathogens Bacteriophages shift the focus of the mammalian microbiota
October 25, 2018 Breck A. Duerkop
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10.1371/journal.ppat.1007297

PLOS Pathogens Pathogen-based precision medicine for drug-resistant tuberculosis
October 18, 2018 Matthias I. Gröschel, Timothy M. Walker, Tjip S. van der Werf, Christoph Lange, Stefan Niemann, Matthias Merker
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10.1371/journal.ppat.1007215

PLOS Pathogens There was collusion: Microbes in inflammatory bowel disease
September 20, 2018 Serre-Yu Wong, Ken Cadwell
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10.1371/journal.ppat.1006990

PLOS Pathogens CRISPR-Cas antimicrobials: challenges and future prospects
June 14, 2018 Elizabeth Pursey, David Sünderhauf, William Gaze, Edze Westra, Stineke van Houte
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flickr, NIAID (2010)

PLOS Pathogens Tuberculosis, war, and refugees: Spotlight on the Syrian humanitarian crisis
June 7, 2018 Mohamad Bachar Ismail, Rayane Rafei, Fouad Dabboussi, Monzer Hamze
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10.1371/journal.ppat.1006924

PLOS Pathogens Antibiotic interceptors: Creating safe spaces for bacteria
April 19, 2018 Akshay Sabnis, Elizabeth V. K. Ledger, Vera Pader, Andrew M. Edwards
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10.1371/journal.ppat.1006805

PLOS Pathogens Wicked: The untold story of ciprofloxacin
March 1, 2018 Zachary C. Conley, Truston J. Bodine, Andrew Chou, Lynn Zechiedrich
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amboo who?, flickr

PLOS Pathogens Sex differences shape the response to infectious diseases
December 28, 2017 Molly Ingersoll
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Freyberg Z, Harvill ET (2017)

PLOS Pathogens Pathogen manipulation of host metabolism: A common strategy for immune evasion
December 7, 2017 Zachary Freyberg, Eric Harvill
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10.1371/journal.ppat.1006657

PLOS Pathogens Orientia tsutsugamushi: A neglected but fascinating obligate intracellular bacterial pathogen
December 7, 2017 Jeanne Salje
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10.1371/journal.ppat.1006622

PLOS Pathogens Irruptive mammal host populations shape tularemia epidemiology
November 16, 2017 Juan J. Luque-Larena, François Mougeot, Beatriz Arroyo, Mª Dolors Vidal, Ruth Rodríguez-Pastor, Raquel Escudero, Pedro Anda, Xavier Lambin
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10.1371/journal.ppat.1006573

PLOS Pathogens The gastric microbiome, its interaction with Helicobacter pylori, and its potential role in the progression to stomach cancer
October 5, 2017 Jennifer M. Noto, Richard M. Peek Jr.
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10.1371/journal.ppat.1006480

PLOS Pathogens The microbiome and the hallmarks of cancer
September 21, 2017 Laura E. Fulbright, Melissa Ellermann, Janelle C. Arthur
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10.1371/journal.ppat.1006424

PLOS Pathogens Multikingdom microscale models
August 24, 2017 Layla Barkal, Erwin Berthier, Ashleigh Theberge, Nancy Keller, David Beebe
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10.1371/journal.ppat.1006369

PLOS Pathogens Colonizing opportunistic pathogens (COPs): The beasts in all of us
August 10, 2017 Lance B. Price, Bruce A. Hungate, Benjamin J. Koch, Gregg S. Davis, Cindy M. Liu
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10.1371/journal.ppat.1006342

PLOS Pathogens The microbiome in hematopoietic stem cell transplant recipients and cancer patients: opportunities for clinical advances that reduce infection
June 29, 2017 Andrew Y. Koh
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10.1371/journal.ppat.1006333

PLOS Pathogens Signaling C-type lectin receptors in antimycobacterial immunity
June 22, 2017 Mohlopheni J. Marakalala, Hlumani Ndlovu
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10.1371/journal.ppat.1006325

PLOS Pathogens T6SS: The bacterial “fight club” in the host gut
June 8, 2017 Thibault G. Sana, Kyler A. Lugo, Denise M. Monack
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10.1371/journal.ppat.1006306

PLOS Pathogens Bacterial outer membrane vesicles at the plant–pathogen interface
June 1, 2017 Leron Katsir, Ofir Bahar
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10.1371/journal.ppat.1006287

PLOS Pathogens New opportunities and challenges to engineer disease resistance in cassava, a staple food of African small-holder farmers
May 11, 2017 Rebecca S. Bart, Nigel J. Taylor
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10.1371/journal.ppat.1006277

PLOS Pathogens Drosophila as a model for homeostatic, antibacterial, and antiviral mechanisms in the gut
May 4, 2017 Xi Liu, Jeffrey Hodgson, Nicolas Buchon
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Phillips KE, Satchell KJF (2017)

PLOS Pathogens Vibrio vulnificus: From Oyster Colonist to Human Pathogenrn
January 5, 2017 Kelsey Phillips, Karla Satchell
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10.1371/journal.ppat.1006012

PLOS Pathogens Convergence of Staphylococcus aureus Persister and Biofilm Research: Can Biofilms Be Defined as Communities of Adherent Persister Cells?
December 29, 2016 Elaine Waters, Sarah Rowe, James O'Gara, Brian Conlon
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10.1371/journal.ppat.1005997

PLOS Pathogens The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy
December 22, 2016 Quang N. Nguyen, Jonathon E. Himes, David R. Martinez, Sallie R. Permar
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10.1371/journal.ppat.1005863

PLOS Pathogens Carrion’s Disease: More Than a Sand Fly–Vectored Illness
October 13, 2016 Maria Pons, Cláudia Gomes, Juana del Valle-Mendoza, Joaquim Ruiz
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10.1371/journal.ppat.1005837

PLOS Pathogens Community-Associated Methicillin-Resistant Staphylococcus aureus: An Enemy amidst Us
October 6, 2016 Eric Kong, Jennifer Johnson, Mary Ann Jabra-Rizk
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10.1371/journal.ppat.1005828

PLOS Pathogens Fungal Super Glue: The Biofilm Matrix and Its Composition, Assembly, and Functions
September 29, 2016 Kaitlin Mitchell, Robert Zarnowski, David Andes
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10.1371/journal.ppat.1005807

PLOS Pathogens Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity
September 22, 2016 Ryan Gaudet, Scott Gray-Owen
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10.1371/journal.ppat.1005797

PLOS Pathogens Compromised Defenses: Exploitation of Epithelial Responses During Viral–Bacterial Co-Infection of the Respiratory Tract
September 15, 2016 Jeffrey Melvin, Jennifer Bomberger
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Amboo Whoo Flickr.com

PLOS Pathogens Rampant Cheating by Pathogens?
September 8, 2016 Ethan A. Rundell, Saria A. McKeithen-Mead, Barbara I. Kazmierczak
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10.1371/journal.ppat.1005682

PLOS Pathogens Conquering Neutrophils
July 28, 2016 Simon Döhrmann, Jason Cole, Victor Nizet
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Zapotoczna M, et al (2016)

PLOS Pathogens Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation
July 21, 2016 Marta Zapotoczna, Eoghan O'Neill, James O'Gara
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10.1371/journal.ppat.1005633

PLOS Pathogens Commensal–Pathogen Interactions along the Human Nasal Passages
July 7, 2016 Silvio D. Brugger, Lindsey Bomar, Katherine P. Lemon
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10.1371/journal.ppat.1005624

PLOS Pathogens IL-26: An Emerging Proinflammatory Member of the IL-10 Cytokine Family with Multifaceted Actions in Antiviral, Antimicrobial, and Autoimmune Responses
June 23, 2016 Emmanuel Stephen-Victor, Helmut Fickenscher, Jagadeesh Bayry
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10.1371/journal.ppat.1005596

PLOS Pathogens Immune Sensing of Lipopolysaccharide in Plants and Animals: Same but Different
June 9, 2016 Stefanie Ranf
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10.1371/journal.ppat.1005598

PLOS Pathogens Anti-infective Surface Coatings: Design and Therapeutic Promise against Device-Associated Infections
June 2, 2016 Bryan R. Coad, Hans J. Griesser, Anton Y. Peleg, Ana Traven
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Jakobson, Tullman-Ercek

PLOS Pathogens Dumpster Diving in the Gut: Bacterial Microcompartments as Part of a Host-Associated Lifestyle
May 12, 2016 Christopher Jakobson, Danielle Tullman-Ercek
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10.1371/journal.ppat.1005488

PLOS Pathogens Tick–Host–Pathogen Interactions: Conflict and Cooperation
April 21, 2016 José de la Fuente, Margarita Villar, Alejandro Cabezas-Cruz, Agustin Estrada-Pena, Nieves Ayllon, Pilar Alberdi
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10.1371/journal.ppat.1005479

PLOS Pathogens Modulation of Host Angiogenesis as a Microbial Survival Strategy and Therapeutic Target
April 14, 2016 Nir Osherov, Ronen Ben-Ami
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10.1371/journal.ppat.1005397

PLOS Pathogens Go Forth and Colonize: Dispersal from Clinically Important Microbial Biofilms
February 18, 2016 Priya Uppuluri, Jose L. Lopez-Ribot
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10.1371/journal.ppat.1005330

PLOS Pathogens Impact of Bacterial and Human Genetic Variation on Staphylococcus aureus Infections
January 14, 2016 Julia A. Messina, Joshua T. Thaden, Batu K. Sharma-Kuinkel, Vance G. Fowler
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10.1371/journal.ppat.1005295

PLOS Pathogens SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection
January 7, 2016 Chynna N. Broxton, Valeria C. Culotta
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10.1371/journal.ppat.1005282

PLOS Pathogens Phages Fight Back: Inactivation of the CRISPR-Cas Bacterial Immune System by Anti-CRISPR Proteins
January 7, 2016 Karen L. Maxwell
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10.1371/journal.ppat.1005258

PLOS Pathogens Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat
December 31, 2015 Laura M. Filkins, George A. O’Toole
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10.1371/journal.ppat.1005208

PLOS Pathogens The Divergent Intracellular Lifestyle of Francisella tularensis in Evolutionarily Distinct Host Cells
December 3, 2015 Mateja Ozanic, Valentina Marecic, Yousef Abu Kwaik, Marina Santic
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10.1371/journal.ppat.1005176

PLOS Pathogens Leptospira and Bats: Story of an Emerging Friendship
November 12, 2015 Muriel Dietrich, Kristin Mühldorfer, Pablo Tortosa, Wanda Markotter
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10.1371/journal.ppat.1005156

PLOS Pathogens Dimensions of Horizontal Gene Transfer in Eukaryotic Microbial Pathogens
October 29, 2015 Emile Gluck-Thaler, Jason C. Slot
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10.1371/journal.ppat.1005157

PLOS Pathogens A Gut Odyssey: The Impact of the Microbiota on Clostridium difficile Spore Formation and Germination
October 15, 2015 Aimee Shen
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10.1371/journal.ppat.1003616

PLOS Pathogens Streptococcus mutans, Candida albicans, and the Human Mouth: A Sticky Situation
October 17, 2013 Khalid H. Metwalli, Shariq A. Khan, Bastiaan P. Krom, Mary Ann Jabra-Rizk
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10.1371/journal.ppat.1004201

PLOS Pathogens Microbial Egress: A Hitchhiker’s Guide to Freedom
July 24, 2014 Ana Traven, Thomas Naderer
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10.1371/journal.ppat.1004062

PLOS Pathogens The Emerging Role of Urease as a General Microbial Virulence Factor
May 15, 2014 Julian Rutherford
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10.1371/journal.ppat.1004221

PLOS Pathogens The Wide World of Ribosomally Encoded Bacterial Peptides
July 31, 2014 Rebecca Flaherty, Stefan Freed, Shaun Lee
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10.1371/journal.ppat.1003967

PLOS Pathogens The 2010 Cholera Outbreak in Haiti: How Science Solved a Controversy
April 3, 2014 Fabini Orata, Paul Keim, Yan Boucher
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10.1371/journal.ppat.1004219

PLOS Pathogens Bacteriophages as Vehicles for Antibiotic Resistance Genes in the Environment
July 31, 2014 Jose Luis Balcazar
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10.1371/journal.ppat.1004356

PLOS Pathogens Adaptive Prediction As a Strategy in Microbial Infections
October 2, 2014 Sascha Brunke, Bernhard Hube
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10.1371/journal.ppat.1004252

PLOS Pathogens Disruption of Fas-Fas Ligand Signaling, Apoptosis, and Innate Immunity by Bacterial Pathogens
August 7, 2014 Adam Caulfield, Wyndham Lathem
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10.1371/journal.ppat.1004255

PLOS Pathogens Hell’s BELs: Bacterial E3 Ligases That Exploit the Eukaryotic Ubiquitin Machinery
August 14, 2014 Jon Huibregtse, John Rohde
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10.1371/journal.ppat.1004409

PLOS Pathogens Multiple Roles of the Cytoskeleton in Bacterial Autophagy
November 20, 2014 Serge Mostowy
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10.1371/journal.ppat.1004349

PLOS Pathogens Teaching Fido New ModiFICation Tricks
September 25, 2014 Jonathan Cruz, Nancy Woychik
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10.1371/journal.ppat.1004299

PLOS Pathogens Regulatory RNAs Involved in Bacterial Antibiotic Resistance
August 28, 2014 David Lalaouna, Alex Eyraud, Svetlana Chabelskaya, Brice Felden, Eric Masse
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10.1371/journal.ppat.1004472

PLOS Pathogens Microbial Urease in Health and Disease
December 11, 2014 Diego Mora, Stefania Arioli
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10.1371/journal.ppat.1004582

PLOS Pathogens Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis
January 29, 2015 Soumya Chatterjee, Thomas Nutman
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10.1371/journal.ppat.1004866

PLOS Pathogens Host Delivery of Favorite Meals for Intracellular Pathogens
June 25, 2015 Yousef Abu Kwaik, Dirk Bumann
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10.1371/journal.ppat.1004644

PLOS Pathogens Bacterial Immune Evasion through Manipulation of Host Inhibitory Immune Signaling
March 5, 2015 Kristof Van Avondt, Nina M. Sorge, Linde Meyaard
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10.1371/journal.ppat.1004847

PLOS Pathogens Battling Phages: How Bacteria Defend against Viral Attack
June 11, 2015 Kimberley Seed
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10.1371/journal.ppat.1004661

PLOS Pathogens The Great Escape: Pathogen Versus Host
March 12, 2015 Eric Kong, Mary Ann Jabra-Rizk
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10.1371/journal.ppat.1004678

PLOS Pathogens Antimicrobial-Induced DNA Damage and Genomic Instability in Microbial Pathogens
March 26, 2015 Rebecca S. Shapiro
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10.1371/journal.ppat.1004952

PLOS Pathogens Periodontal Diseases: Bug Induced, Host Promoted
July 30, 2015 Shariq Khan, Eric Kong, Timothy Meiller, Mary Ann Jabra-Rizk
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10.1371/journal.ppat.1004923

PLOS Pathogens The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease
July 9, 2015 Robert Dickson, Gary Huffnagle
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amboo who?, flickr

PLOS Pathogens The Skin Microbiome: A Focus on Pathogens and Their Association with Skin Disease
November 13, 2014 Keisha Findley, Elizabeth Grice
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10.1371/journal.ppat.1004947

PLOS Pathogens N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens
July 30, 2015 Shamoon Naseem, James B. Konopka
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10.1371/journal.ppat.1004944

PLOS Pathogens Cross Kingdom Activators of Five Classes of Bacterial Effectors
July 23, 2015 David Anderson, Jimmy Feix, Dara Frank
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amboo who?, flickr

PLOS Pathogens Implication of Gut Microbiota in Nonalcoholic Fatty Liver Disease
January 27, 2015 jerome boursier, Anna Mae Diehl
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10.1371/journal.ppat.1005113

PLOS Pathogens Chronobiomics: The Biological Clock as a New Principle in Host–Microbial Interactions
October 8, 2015 Christoph Thaiss, Maayan Levy, Eran Elinav
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10.1371/journal.ppat.1004981

PLOS Pathogens Illuminating Targets of Bacterial Secretion
August 6, 2015 Roger Pechous, William Goldman
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Alsteens D, Beaussart A, El-Kirat-Chatel S, Sullan RMA, Dufrêne YF (2013)

PLOS Pathogens Atomic Force Microscopy: A New Look at Pathogens
September 5, 2013 David Alsteens, Audrey Beaussart, Sofiane El-Kirat-Chatel, Ruby May A. Sullan, Yves F. Dufrêne
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10.1371/journal.ppat.1003447

PLOS Pathogens Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions
August 15, 2013 Hélène Tournu, Alessandro Fiori, Patrick Van Dijck
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10.1371/journal.ppat.1002096

PLOS Pathogens Impact of Endofungal Bacteria on Infection Biology, Food Safety, and Drug Development
June 30, 2011 Gerald Lackner, Christian Hertweck
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amboo who?, flickr

PLOS Pathogens Livestock-Associated Staphylococcus aureus: The United States Experience
February 5, 2015 Tara Smith
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10.1371/journal.ppat.1003538

PLOS Pathogens Self and Non-self Discrimination of Intracellular Membranes by the Innate Immune System
September 19, 2013 Jorn Coers
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10.1371/journal.ppat.1003433

PLOS Pathogens Role of the Nervous System in the Control of Proteostasis during Innate Immune Activation: Insights from C. elegans
August 8, 2013 Alejandro Aballay
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10.1371/journal.ppat.1003143

PLOS Pathogens Bacterial Survival Amidst an Immune Onslaught: The Contribution of the Staphylococcus aureus Leukotoxins
February 21, 2013 Francis Alonzo, Victor Torres
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10.1371/journal.ppat.1002907

PLOS Pathogens How to Make It in the Urinary Tract: A Tutorial by Escherichia coli
October 4, 2012 Ine Jorgensen, Patrick Seed
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10.1371/journal.ppat.1002823

PLOS Pathogens Five Mechanisms of Manipulation by Bacterial Effectors: A Ubiquitous Theme
August 23, 2012 David Anderson, Dara Frank
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10.1371/journal.ppat.1000949

PLOS Pathogens The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts
August 12, 2010 Eric P. Skaar
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amboo who?, flickr

PLOS Pathogens Igniting the Fire: Staphylococcus aureus Virulence Factors in the Pathogenesis of Sepsis
February 13, 2014 Michael Powers, Juliane Bubeck Wardenburg
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amboo who?, flickr

PLOS Pathogens Risks of Antibiotic Exposures Early in Life on the Developing Microbiome
July 2, 2015 Anjelique Schulfer, Martin Blaser
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10.1371/journal.ppat.1003794

PLOS Pathogens Host Susceptibility Factors to Bacterial Infections in Type 2 Diabetes
December 26, 2013 Yunn-Hwen Gan
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10.1371/journal.ppat.1003740

PLOS Pathogens Disease to Dirt: The Biology of Microbial Amyloids
November 21, 2013 David Hufnagel, Çagla Tükel, Matthew Chapman
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10.1371/journal.ppat.1003730

PLOS Pathogens Colonization Resistance: Battle of the Bugs or Ménage à Trois with the Host?
November 21, 2013 Alanna Spees, Christopher Lopez, Dawn Kingsbury, Sebastian Winter, Andreas Baumler
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amboo who?, flickr

PLOS Pathogens Microbial Endocrinology in the Microbiome-Gut-Brain Axis: How Bacterial Production and Utilization of Neurochemicals Influence Behavior
November 14, 2013 Mark Lyte
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10.1371/journal.ppat.1003808

PLOS Pathogens Host Defense via Symbiosis in Drosophila
December 26, 2013 Phineas Hamilton, Steve Perlman
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10.1371/journal.ppat.1003765

PLOS Pathogens CRISPR-Cas Immunity against Phages: Its Effects on the Evolution and Survival of Bacterial Pathogens
December 12, 2013 Luciano Marraffini
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10.1371/journal.ppat.1003724

PLOS Pathogens The Biology and Taxonomy of Head and Body Lice—Implications for Louse-Borne Disease Prevention
November 14, 2013 Denise Bonilla, Lance Durden, Marina Eremeeva, Gregory Dasch
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amboo who?, flickr

PLOS Pathogens DNA Damage Repair and Bacterial Pathogens
November 7, 2013 Darja Žgur-Bertok
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10.1371/journal.ppat.1003621

PLOS Pathogens Alternative Roles for CRISPR/Cas Systems in Bacterial Pathogenesis
October 17, 2013 Timothy Sampson, David Weiss
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10.1371/journal.ppat.1003603

PLOS Pathogens Antivirulence Therapy for Animal Production: Filling an Arsenal with Novel Weapons for Sustainable Disease Control
October 10, 2013 Tom Defoirdt
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10.1371/journal.ppat.1003540

PLOS Pathogens Bringing Culture to the Uncultured: Coxiella burnetii and Lessons for Obligate Intracellular Bacterial Pathogens
September 5, 2013 Anders Omsland, Ted Hackstadt, Robert Heinzen
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amboo who?, flickr

PLOS Pathogens Pertussis: Challenges Today and for the Future
July 25, 2013 James Cherry
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10.1371/journal.ppat.1003388

PLOS Pathogens Stress Relief during Host Infection: The Phage Shock Protein Response Supports Bacterial Virulence in Various Ways
July 11, 2013 Andrew Darwin
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10.1371/journal.ppat.1003340

PLOS Pathogens Experimental Evolution of Pathogenesis: “Patient” Research
May 30, 2013 Alexander Ensminger
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10.1371/journal.ppat.1003288

PLOS Pathogens A Disconnect between the Neurospirochetoses in Humans and Rodent Models of Disease
April 11, 2013 Jorge Benach, Juan Garcia-Monco
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amboo who? Flickr

PLOS Pathogens Chemical Signals and Mechanosensing in Bacterial Responses to Their Environment
August 27, 2015 Henny C. van der Mei, Akshay Harapanahalli, Jessica Younes, Elaine Allan, Henk Busscher
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10.1371/journal.ppat.1003126

PLOS Pathogens Proteins Secreted via the Type II Secretion System: Smart Strategies of Vibrio cholerae to Maintain Fitness in Different Ecological Niches
February 21, 2013 Aleksandra Sikora
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10.1371/journal.ppat.1002821

PLOS Pathogens Bacterial Cell Surface Heterogeneity: A Pathogen’s Disguise
August 30, 2012 Henny Van der Mei, Henk Busscher
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amboo who?, flickr

PLOS Pathogens Type III Secretion in Yersinia: Injectisome or Not?
May 10, 2012 Tomas Edgren, Åke Forsberg, Roland Rosqvist, Hans Wolf-Watz
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10.1371/journal.ppat.1002440

PLOS Pathogens How Do Bacteria Know They Are on a Surface and Regulate Their Response to an Adhering State?
January 26, 2012 Henk Busscher, Henny Van der Mei
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10.1371/journal.ppat.1002312

PLOS Pathogens Microbial Spy Games and Host Response: Roles of a Pseudomonas aeruginosa Small Molecule in Communication with Other Species
November 17, 2011 Lucja Jarosz, Ekaterina Ovchinnikova, Michael Meijler, Bastiaan Krom
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10.1371/journal.ppat.1002121

PLOS Pathogens “Persisters”: Survival at the Cellular Level
July 28, 2011 Clinton Dawson, Chaidan Intapa, Mary Ann Jabra-Rizk
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10.1371/journal.ppat.1003661

PLOS Pathogens Sensing of the Microbial Neighborhood by Candida albicans
October 31, 2013 Emily M. Mallick, Richard J. Bennett
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10.1371/journal.ppat.1003612

PLOS Pathogens Fungal Adenylyl Cyclase Acts As a Signal Sensor and Integrator and Plays a Central Role in Interaction with Bacteria
October 10, 2013 Yue Wang
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10.1371/journal.ppat.1002323

PLOS Pathogens Five Questions about Non-Mevalonate Isoprenoid Biosynthesis
December 22, 2011 Audrey Odom
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10.1371/journal.ppat.1003144

PLOS Pathogens Noncanonical Inflammasomes: Caspase-11 Activation and Effector Mechanisms
February 28, 2013 Denise Monack, Petr Broz
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amboo who?, flickr

PLOS Pathogens Toll-Like Receptors Promote Mutually Beneficial Commensal-Host Interactions
July 26, 2012 June Round, Jason Kubinak
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10.1371/journal.ppat.1000510

PLOS Pathogens The Inflammasomes
December 24, 2009 Mohamed Lamkanfi, Vishva M. Dixit
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10.1371/journal.ppat.1003424

PLOS Pathogens Understanding Human Variation in Infectious Disease Susceptibility through Clinical and Cellular GWAS
August 1, 2013 Dennis Ko, Thomas Urban
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10.1371/journal.ppat.1002349

PLOS Pathogens Zebrafish: A See-Through Host and a Fluorescent Toolbox to Probe Host–Pathogen Interaction
January 5, 2012 David Tobin, Robin May, Robert Wheeler
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10.1371/journal.ppat.1001067

PLOS Pathogens Antimicrobial Peptides: Primeval Molecules or Future Drugs?
October 28, 2010 Brian M. Peters, Mark E. Shirtliff, Mary Ann Jabra-Rizk
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amboo who?, flickr

PLOS Pathogens The Microbiota and Allergies/Asthma
May 27, 2010 Gary B. Huffnagle
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10.1371/journal.ppat.1002887

PLOS Pathogens Copper at the Front Line of the Host-Pathogen Battle
September 20, 2012 Richard Festa, Dennis Thiele
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10.1371/journal.ppat.1000886

PLOS Pathogens Candida albicans Interactions with Bacteria in the Context of Human Health and Disease
April 29, 2010 Diana K. Morales, Deborah A. Hogan
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10.1371/journal.ppat.1003080

PLOS Pathogens Innate Sensing of Chitin and Chitosan
January 10, 2013 Chelsea Bueter, Charles Specht, Stuart Levitz
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10.1371/journal.ppat.1003417

PLOS Pathogens Signalling C-Type Lectins in Antimicrobial Immunity
July 25, 2013 Rebecca Drummond, Gordon Brown
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10.1371/journal.ppat.1003230

PLOS Pathogens Polyphosphate and Its Diverse Functions in Host Cells and Pathogens
May 2, 2013 Silvia Moreno, Roberto Docampo
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10.1371/journal.ppat.1001310

PLOS Pathogens Innate Immune Sensing of DNA
April 21, 2011 Shruti Sharma, Katherine A. Fitzgerald
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amboo who?, flickr

PLOS Pathogens Sleeping with the Enemy: How Intracellular Pathogens Cope with a Macrophage Lifestyle
March 22, 2012 Emily Thi, Ulrike Lambertz, Neil Reiner
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10.1371/journal.ppat.1002804

PLOS Pathogens Host Defense and Tolerance: Unique Challenges in the Placenta
August 9, 2012 Varvara Zeldovich, Anna Bakardjiev
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10.1371/journal.ppat.1003552

PLOS Pathogens Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens
October 3, 2013 Jason Brunton, Shaun Steele, Benjamin Ziehr, Nathaniel Moorman, Thomas Kawula
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10.1371/journal.ppat.1000470

PLOS Pathogens The Photobiology of Microbial Pathogenesis
November 26, 2009 Alexander Idnurm, Sean Crosson
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10.1371/journal.ppat.1002893

PLOS Pathogens A Population Genomics Perspective on the Emergence and Adaptation of New Plant Pathogens in Agro-Ecosystems
September 27, 2012 Eva Stukenbrock, Thomas Bataillon
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10.1371/journal.ppat.1003026

PLOS Pathogens The Role of Auxin-Cytokinin Antagonism in Plant-Pathogen Interactions
November 29, 2012 Muhammad Naseem, Thomas Dandekar
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10.1371/journal.ppat.1000788

PLOS Pathogens Quantitative Comparison of HTLV-1 and HIV-1 Cell-to-Cell Infection with New Replication Dependent Vectors
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PLOS Pathogens Emerging Infectious Diseases: Threats to Human Health and Global Stability
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PLOS Pathogens The Role of Mast Cells in the Defence against Pathogens
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PLOS Pathogens Conflicting Interests in the Pathogen–Host Tug of War: Fungal Micronutrient Scavenging Versus Mammalian Nutritional Immunity
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PLOS Pathogens Putting Fungi to Work: Harvesting a Cornucopia of Drugs, Toxins, and Antibiotics
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PLOS Pathogens Mycobacteriophages: Windows into Tuberculosis
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PLOS Pathogens The HMW1C-Like Glycosyltransferases—An Enzyme Family with a Sweet Tooth for Simple Sugars
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PLOS Pathogens Oral Bacteria and Cancer
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Explore Pearls

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Speaking of Medicine Lessons that Last, and Last, and Last: 400 Pearls and Still Counting
January 5, 2017 Joseph Heitman
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