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When global policymakers address the health and economic impact of the soil-transmitted helminth infections, they generally refer to the "unholy trinity" of ascariasis, hookworm infection, and trichuriasis. However, increasing information suggests that strongyloidiasis is an important fourth soil-transmitted helminthiasis. There are many reasons for the global neglect of strongyloidiasis, not the least of which is the inconvenient truth that there are little or no global burden of disease data for this infection, nor even any accurate accounting for the actual number of people infected. We also know very little about the true geographic distribution of strongyloidiasis. This special collection will help to highlight this somewhat mysterious yet very important neglected tropical disease, its enormous potential global impact on human health, and the urgent need for basic and applied research.

Image Credit: Maria Gobbo, Centre for Tropical Diseases Verona, Italy

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Filariform (L3) larvae of Strongyloides stercoralis obtained from a stool culture

Bisoffi et al.
PLOS Collections Blog - Medicine & Health Sciences


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