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Biology & Life Sciences

Triple drug (IDA) mass drug administration for elimination of lymphatic filariasis

This collection reports results of clinical trials and community studies of the safety, efficacy, and acceptability of the triple drug regimen IDA (ivermectin plus DEC and Albendazole) as a mass drug administration (MDA) regimen for lymphatic filariasis (LF) elimination programmes. As a group, these papers provide a comprehensive record of how these linked studies helped IDA to make the transition from research discovery to policy change and implementation. Data from these studies supported WHO’s decision to endorse IDA as a tool to accelerate LF elimination in many settings, and tens of millions of people now receive IDA each year.

PLOS Medicine
PLOS Neglected Tropical Diseases

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