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Synthetic Biology

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science.

The Collection has been organized into broad categories focused on DNA synthesis and assembly techniques, the development of libraries for biological parts, the use of synthetic biology in protein engineering applications, work focussing on synthetic life and multicellular systems, gene editing, and the engineering of gene regulatory networks and metabolic pathways. Finally, we include sections that describe enabling technologies such as software and modeling, along with new methods and instrumentation.

Articles in the Synthetic Biology Collection are presented in order of publication date and new articles will be added as they are published. PLOS welcomes submissions in this field.

 

Introductory papers:

 

The PLOS ONE Synthetic Biology Collection: Six Years and Counting
Jean Peccoud, Mark Isalan
PLOS ONE: published August 15, 2012 | info:doi/10.1371/journal.pone.0043231

Synthetic Biology: Mapping the Scientific Landscape
Paul Oldham, Stephen Hall, Geoff Burton
PLOS ONE: published April 23, 2012 | info:doi/10.1371/journal.pone.0034368

 

DNA Synthesis & Assembly

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on DNA Synthesis & Assembly.


Biological Parts

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Biological Parts.


Protein Engineering

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Protein Engineering.


Gene Network Engineering

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Gene Network Engineering.


Metabolic Engineering

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Metabolic Engineering.


Synthetic Life & Multicellular Systems

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Synthetic Life & Multicellular Systems.


Software & Modeling

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Software & Modeling.


Methods & Instruments

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Methods & Instruments.


Genome Editing

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, or computer science. This section features papers on Genome Editing.


Collection Curators:

 

 

Dr. Jean Peccoud, Associate Professor, Virginia Bioinformatics Institute, Virginia Tech 

 

 

 

 

Dr. Mark Isalan, Reader in Systems and Synthetic Biology, Imperial College London