Tuberculosis
Tuberculosis kills more people today than HIV and malaria combined. In 2015, there were an estimated 10.4 million new TB cases worldwide and 1.8 million TB deaths. Six countries account for 60 per cent of the total burden, with India accounting for 27 per cent of the global cases, followed by Indonesia, China, Nigeria, Pakistan and South Africa. Of the 10.4 million new cases, the WHO estimate that only 6.1 million were detected and officially notified. This left a gap of 4.3 million cases that are considered ‘missing’ – either not diagnosed, or not notified to TB control programs. Drug-resistance is a growing threat in many settings, and there is an urgent need for improved drug regimens, vaccines and diagnostics.
The Tuberculosis Channel features articles on all topics relevant to TB research. The Channel editors aim to showcase the most up to date research to assist various stakeholders in the fight against TB, including academics, healthcare workers, policy makers, implementers, patients, and civil society.
Channel Editors
NAID, CC-BY
Dr Soumya Swaminathan
Deputy Director General of Programmes (DDP), World Health Organization
NAID, CC-BY
Dr Madhukar Pai
Director, McGill Global Health Programs
Associate Director, McGill International TB Centre
Channel Administrators
NAID, CC-BY
Sophie Huddart
NAID, CC-BY
Emily MacLean
The Editors are grateful to Sophie Huddart & Emily MacLean, doctoral candidates at McGill University, Montreal, for their contributions to this Channel.
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TB●PPM Learning Network TB●PPM Learning Network
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Frontiers in Cellular and Infection Microbiology Editorial: Cellular and Molecular Mechanisms of Mycobacterium tuberculosis Virulence
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Journal of Clinical Microbiology How Well Do Routine Molecular Diagnostics Detect Rifampin Heteroresistance in Mycobacterium tuberculosis?
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European Respiratory Society Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance
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PLOS Pathogens Tuberculosis drug discovery in the CRISPR era