Biology & Life Sciences

Synthetic Biology: Synthetic Life & Multicellular Systems

Published January 30, 2017 Curated Collections

Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical engineering, and computer science. This section of the Synthetic Biology Collection details papers related to Synthetic Life & Multicellular Systems.

Image Credit: Ivan Morozov (Virginia Bioinformatics Institute) / PLOS

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Research Articles
Pearls
Essay

Research Articles

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10.1371/journal.pcbi.1004685

PLOS Computational Biology Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia
February 1, 2016 Javier Macia, Romilde Manzoni, Núria Conde, Arturo Urrios, Eulàlia de Nadal, Ricard Solé, Francesc Posas
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10.1371/journal.pone.0006946

PLOS ONE Synthetic Morphology Using Alternative Inputs
September 10, 2009 Hiromasa Tanaka, Tau-Mu Yi
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10.1371/journal.pone.0000119

PLOS ONE Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures
December 27, 2006 Fabrizio Gelain, Daniele Bottai, Angleo Vescovi, Shuguang Zhang
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10.1371/journal.pone.0010619

PLOS ONE An Environment-Sensitive Synthetic Microbial Ecosystem
May 12, 2010 Bo Hu, Jin Du, Rui-yang Zou, Ying-jin Yuan
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10.1371/journal.pone.0016292

PLOS ONE Programmable Ligand Detection System in Plants through a Synthetic Signal Transduction Pathway
January 25, 2011 Mauricio Antunes, Kevin Morey, J. Jeff Smith, Kirk Albrecht, Tessa Bowen, Jeffrey Zdunek, Jared Troupe, Matthew Cuneo, Colleen Webb, Homme Hellinga, June Medford
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10.1371/journal.pone.0016791

PLOS ONE Self-Organization, Layered Structure, and Aggregation Enhance Persistence of a Synthetic Biofilm Consortium
February 9, 2011 Katie Brenner, Frances Arnold
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10.1371/journal.pone.0018877

PLOS ONE Towards a Synthetic Chloroplast
April 20, 2011 Christina Agapakis, Henrike Niederholtmeyer, Ramil Noche, Tami Lieberman, Sean Megason, Jeffrey Way, Pamela Silver
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10.1371/journal.pone.0019912

PLOS ONE Design and Synthesis of a Quintessential Self-Transmissible IncX1 Plasmid, pX1.0
May 18, 2011 Lars Hansen, Mikkel Bentzon-Tilia, Sara Bentzon-Tilia, Anders Norman, Louise Rafty, Søren Sørensen
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10.1371/journal.pone.0027062

PLOS ONE Chemical Synthesis of Bacteriophage G4
November 16, 2011 Ruilin Yang, Yonghua Han, Yiwang Ye, Zhimao Jiang, Yuchen Liu, Yaoting Gui, Zhiming Cai
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10.1371/journal.pntd.0001724

PLOS Neglected Tropical Diseases Female-Specific Flightless (fsRIDL) Phenotype for Control of Aedes albopictus
July 10, 2012 Geneviève Labbé, Sarah Scaife, Siân Morgan, Zoë Curtis, Luke Alphey
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10.1371/journal.pcbi.1002579

PLOS Computational Biology Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity
July 19, 2012 Miles Miller, Marc Hafner, Eduardo Sontag, Noah Davidsohn, Sairam Subramanian, Priscilla Purnick, Douglas Lauffenburger, Ron Weiss
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10.1371/journal.pone.0057482

PLOS ONE A Formalized Design Process for Bacterial Consortia That Perform Logic Computing
February 28, 2013 Weiyue Ji, Handuo Shi, Haoqian Zhang, Rui Sun, Jingyi Xi, Dingqiao Wen, Jingchen Feng, Yiwei Chen, Xiao Qin, Yanrong Ma, Wenhan Luo, Linna Deng, Hanchi Lin, Ruofan Yu, Qi Ouyang
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10.1371/journal.pone.0065986

PLOS ONE Multicellular Computing Using Conjugation for Wiring
June 20, 2013 Angel Goni-Moreno, Martyn Amos, Fernando de la Cruz
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10.1371/journal.pcbi.1003110

PLOS Computational Biology A Design Principle of Group-level Decision Making in Cell Populations
June 27, 2013 Koichi Fujimoto, Satoshi Sawai

Pearls

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10.1371/journal.ppat.1003909

PLOS Pathogens Five Things to Know about Genetically Modified (GM) Insects for Vector Control
March 6, 2014 Luke Alphey, Nina Alphey

Essay

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10.1371/journal.pbio.1001323

PLOS Biology Bit by Bit: The Darwinian Basis of Life
May 8, 2012 Gerald Joyce

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