The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Computer & Information Sciences Focus Feature – Protein FunctionsView Collection
This Focus Feature led by Jacquelyn S. Fetrow and Patricia C. Babbitt focuses on understanding the different molecular functions that can exist within a protein superfamily and the features that…
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Earth & Environment Oil SpillsView Collection
Oil Spills cause catastrophic and persistent damage on enormous scales, and have dramatic consequences for both humans and the environment. Research into the consequences of oil spills is multifaceted…
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Medicine & Health Translating the Cancer Genome – Implications for Diagnosis and TreatmentView Collection
Dramatic reductions in the cost of sequencing, as well advances in sequencing technologies, have enabled key insights into the genomic alterations and somatic mutations that lead to cancer and…
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Biology & Life Sciences Cancer ResearchView Collection
Cancers figure among the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths each year. It is expected that annual cancer…
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collection Pearls: PrionsView Collection
PLOS Pathogens presents an Open Access compendium of the "lessons-that-last." This section, founded by Dr. Hiten Madhani and now led by Dr. Joseph Heitman and a team of twelve Pearls…
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Biology & Life Sciences Conservation Stories from the Front LinesView Collection
Scientists tell stories about their work in many ways, in many venues. And though the ups and downs of the research process underlie every scientific publication, they rarely make it into the final…
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Medicine & Health Real-Time Monitoring of Under-Five MortalityView Collection
In most low-income countries, Ministries of Health and their partners must rely on periodic household surveys as their primary population-level source of vital statistics. Recent initiatives around…
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collection PLOS ONE 10 Year Anniversary Collection: Editorial Board FavoritesView Collection
To cap off the PLOS ONE 10 Year Anniversary collection series, we decided to focus our efforts on the PLOS ONE Editorial Board – a sizable group of accomplished scientists that has allowed us…
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Medicine & Health malERA – An updated research agenda for malaria elimination and eradicationView Collection
‘malERA Refresh’ is a forward-looking research and development agenda that accelerates progress towards malaria elimination and global eradication. The malERA Refresh special collection…
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Biology & Life Sciences PLOS iGEM 2015View Collection
The iGEM Foundation is dedicated to the advancement of synthetic biology through the development of open community and collaboration. These aims are shared by PLOS, whose mission is to advance…