The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Research Analysis & Policy Meta-Research: Policy and InterventionsView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Research Analysis & Policy Meta-Research: Evaluation and ScientometricsView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Research Analysis & Policy Meta-Research: Tools for Improving Biomedical ResearchView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Research Analysis & Policy Meta-Research: MethodsView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Medicine & Health The Global Challenges of Noncommunicable DiseasesView Collection
Noncommunicable diseases (NCDs) are responsible for two-thirds of the world's deaths, one-fourth of which occur before the age of 60. Nearly 80% of NCD deaths occur in low- and middle-income…
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Medicine & Health Epidemiological metrics for the HIV epidemicView Collection
Extraordinary progress has been made to halt and reverse the spread of HIV. However, there is still a long way to go to end the epidemic, as called for in the third Sustainable Development…
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Biology & Life Sciences PLOS Biology’s XV Collection: 15 Years of Open ScienceView Collection
To commemorate 15 years of PLOS Biology, this collection will showcase a series of twelve blog posts, one each month, featuring an article selected by one of our hard-working Editorial Board Members…
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Medicine & Health Flubendazole in OnchocerciasisView Collection
Treating onchocerciasis remains a challenge as no drug effectively kills the adult worms. A new orally bioavailable formulation of flubendazole was developed and tested to find out whether it could be…
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Research Analysis & Policy PLOS Pathogens: Research MattersView Collection
PLOS Pathogens presents Research Matters as a means to bridge the gap between academic research and the public. Research Matters provides a forum for active scientists to tell the public how diverse…
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Medicine & Health Cardiovascular DiseasesView Collection
Cardiovascular disease (CVD) is the number one cause of death and disability globally, with an estimated 17.7 million deaths from CVD in 2015. More than three-quarters of CVD deaths occur in low- and…