The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: Improving Quality, Efficiency, Cost Effectiveness, & Demand for Services during an Accelerated Scale-upView Collection
With new HIV infections in Sub-Saharan Africa occurring at a rate of 2.3 million each year, this new collection presents interim results from a large public health intervention of voluntary medical…
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Medicine & Health Editor’s Picks: Co-Infection in Tropical MedicineView Collection
Co-infection with more than one pathogen is a continuing challenge in global health, particularly in regions with multiple endemic infectious diseases. Direct and indirect interactions between…
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Biology & Life Sciences GLBIO 2017View Collection
The 12th Great Lakes Bioinformatics Conference (GLBIO) 2017, organized by the GLBIO Consortium, aimed to provide an interdisciplinary forum for the discussion of research findings and methods in…
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Research Analysis & Policy Meta-Research: Sources of BiasView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Earth & Environment Confronting Climate Change in the Age of DenialView Collection
Most scientists believe that climate change is one of the greatest challenges of our time -- if not the greatest challenge. Yet too often, efforts to communicate science-based information about the…
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Research Analysis & Policy Editor’s Picks: Understanding the Gender Imbalance in STEM FieldsView Collection
Increasing numbers of women are entering science, technology, engineering, and mathematics (STEM) disciplines at undergraduate and graduate levels. However, women remain underrepresented at higher…
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Earth & Environment Open Highlights: Birds, Blooms, and Evolving DiversityView Collection
How the traits that distinguish species develop and diversify over time is a long-standing question in the field of evolutionary biology. This Open Highlight investigates how species have evolved…
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Research Analysis & Policy Publishing Dual Use Research of Concern: A Case StudyView Collection
The implications of publishing dual use research of concern (DURC) continues to be a topic widely and deeply discussed in the scientific community. In a series of Opinion articles, PLOS Pathogens…
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Biology & Life Sciences GIGA: Global Invertebrate Genomics Alliance researchView Collection
GIGA is an international non-profit community of scientists dedicated to promoting genomics research of diverse non-model invertebrate species. Invertebrates comprise over 95% of all animal species…
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Biology & Life Sciences PLOS iGEM 2016View Collection
The iGEM Foundation is dedicated to the advancement of synthetic biology through the development of open community and collaboration. These aims are shared by PLOS, whose mission is to advance…