The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Computer & Information Sciences Editors’ OutlookView Collection
The PLOS Computational Biology Editors' Outlook collection provides diverse mini reviews from members of the Editorial Board on their research areas, and includes discussions of new and future…
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Computer & Information Sciences Bioinformatics: Starting EarlyView Collection
Bioinformatics is being introduced into the school curriculum earlier and earlier as the field matures. PLOS Computational Biology's Education section introduces a new collection, Bioinformatics…
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Computer & Information Sciences BiocuratorsView Collection
The number and scope of scientific databases has soared in recent years, creating a new profession, the biocurator. These "museum catalogers of the Internet age" face a continuous struggle…
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Computer & Information Sciences Focus Feature – Protein FunctionsView Collection
This Focus Feature led by Jacquelyn S. Fetrow and Patricia C. Babbitt focuses on understanding the different molecular functions that can exist within a protein superfamily and the features that…
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Biology & Life Sciences Focus Feature – Network Approaches and Applications in BiologyView Collection
This Focus Feature addresses some of the most exciting current opportunities and challenges in the field of Network Biology. The collection of articles includes both primary research papers and…
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Computer & Information Sciences Open Source Toolkit: HardwareView Collection
The Open Source Toolkit has migrated to PLOS Channels. PLEASE VISIT THE OPEN SOURCE TOOLKIT CHANNEL FOR THE LATEST OPEN SOURCE RESEARCH…
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Biology & Life Sciences RosettaCon 2014View Collection
The Rosetta macromolecular modeling software is a versatile, rapidly developing set of tools that are now being routinely utilized to address state-of-the-art research challenges in academia and…
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Biology & Life Sciences Synthetic Biology: Software & ModelingView Collection
Synthetic Biology is an emerging, trans-disciplinary field at the intersection between many engineering and scientific disciplines such as biology, chemical engineering, chemistry, electrical…
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Biology & Life Sciences GLBIO/CCBC 2016 – Bioinformatics and Computational BiologyView Collection
The first joint Great Lakes Bioinformatics (GLBio) and the Canadian Computational Biology Conference 2016 (GLBIO/CCBC) took place in Toronto from May 16th to 19th. The conference was organized by the…
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Computer & Information Sciences Focus Feature – Genome Landscapes and Phenotype Prediction of DiseaseView Collection
This Focus Feature led by Rachel Karchin and Ruth Nussinov highlights strategies to predict the phenotypic disease consequences of human germline and somatic variation. The rapid growth in genomic…