The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Biology & Life Sciences RECOMB Regulatory Genomics and Systems Biology 2009View Collection
In a joint venture between PLOS and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB…
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Computer & Information Sciences Conference PostcardsView Collection
Conference Postcards are designed to vividly recount to those not at a conference what happened at the event that was scientifically noteworthy. Postcards aim to be a departure from routine conference…
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Computer & Information Sciences The Roots of BioinformaticsView Collection
This collection of essays from prominent workers in the field of bioinformatics relates how selected scientific, technological, economic, and even cultural threads came to influence the development of…
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Computer & Information Sciences Proceedings of the Third International Barcode of Life Conference Mexico CityView Collection
"DNA barcoding" was proposed formally in 2003 as a technique for species diagnosis and identification using short standardized gene regions. Early conferences focused on the degree to which…
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Biology & Life Sciences The DREAM Systems Biology ChallengesView Collection
The Dialogue for Reverse Engineering Assessments and Methods (DREAM) grew as a community effort to catalyze discussion about the design, application, and assessment of systems biology models through…
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Computer & Information Sciences BiocuratorsView Collection
The number and scope of scientific databases has soared in recent years, creating a new profession, the biocurator. These "museum catalogers of the Internet age" face a continuous struggle…
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Computer & Information Sciences Editors’ OutlookView Collection
The PLOS Computational Biology Editors' Outlook collection provides diverse mini reviews from members of the Editorial Board on their research areas, and includes discussions of new and future…
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Computer & Information Sciences Bioinformatics: Starting EarlyView Collection
Bioinformatics is being introduced into the school curriculum earlier and earlier as the field matures. PLOS Computational Biology's Education section introduces a new collection, Bioinformatics…
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Computer & Information Sciences Focus Feature – Protein FunctionsView Collection
This Focus Feature led by Jacquelyn S. Fetrow and Patricia C. Babbitt focuses on understanding the different molecular functions that can exist within a protein superfamily and the features that…
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Biology & Life Sciences Focus Feature – Network Approaches and Applications in BiologyView Collection
This Focus Feature addresses some of the most exciting current opportunities and challenges in the field of Network Biology. The collection of articles includes both primary research papers and…