PLOS Calls for Papers

Showcase your research in a topical and timely PLOS Collection. Our journals partner with experienced Guest Editors to call for papers from the research community. The Guest Editors select articles for inclusion in the finished Collection or Special Issue.


Understanding and Preventing Suicide

Suicide is a major public health issue and is a frequent cause of death worldwide. Risk of suicide is determined by a complex interaction of predisposing and precipitating determinants and understanding the issue requires an appreciation of the interplay between societal, psychological, spiritual, clinical, and biological factors. The broad scope of PLOS ONE facilitates publication of the interdisciplinary research necessary to better understand and prevent suicidal behaviour.

Coming Soon


  • To be announced!


Now Open


Medicine & Health Sciences

Cancer Advances: Clinically Applicable Insights into Early Detection and Minimal Residual Disease

PLOS Medicine


Global Child Health: From Birth to Adolescence and Beyond

PLOS Medicine


Understanding and Preventing Suicide



Health and Health Care in Gender Diverse Communities



Cancer Metastasis



Drug Delivery



Cognitive Psychology


Biology & Life Sciences

Modeling Cell Proliferation and the Cell Microenvironment


Earth & Environmental Sciences

Plant Phenomics and Precision Agriculture



Rewilding and Restoration



Freshwater Ecosystems


Physics, Chemistry & Materials

Coming soon!


Closed Calls

The deadlines for these Calls for Papers have now passed, but we always welcome your research in any of these areas.

Collection publishing: To be Announced 2020

PLOS Medicine


Collection publishing: To Be Announced 2020

PLOS Neglected Tropical Diseases PLOS ONE


Collection publishing: To Be Announced 2020

PLOS Medicine


Collection publishing: November 2020

PLOS Medicine & PLOS ONE


Collection publishing: To be Announced 2020



Collection publishing: November 2020



Collection publishing: December 2020



Collection publishing: TBD 2020

PLOS Biology


Collection publishing: January 2021


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Microbial Ecology of Changing Environments

From the response and contribution of microbes to climate change to the impacts on microbes of acute disturbance events, and from community interactions in naturally dynamic environments to the effects of global change on plant and wildlife disease epidemiology, our Collection brings together research from across the diverse, interwoven strands of microbial ecology.

Health Inequities and Disparities Research

These papers include health equities due to race/ethnicity, socio-economic status, sexual or gender minority identification, immigrant status (including undocumented immigrants), incarceration, socio-economic status, and country of residence. This thought-provoking collection is an important contribution to the field of health inequities and disparities and will expand our understanding of how we define and study these topics.

Digital Health Technology

Digital health technologies bring together engineers, computer scientists, behavioral scientists, public health researchers, and clinicians to design technological solutions for patient care and health systems management. This PLOS ONE collection highlights a broad range of digital health research, from technology development to translation of data insights into action, that closes the loop between stakeholders and technologies.

Blood-Brain Barrier Biology in Health and Pathology

The strict regulation of the microenvironment by the blood-brain barrier is a key component of central nervous system function. Changes in the structure and function of this unique and dynamic interface are implicated in a variety of neurological disorders, and the high selectivity of the blood-brain barrier presents both challenges and opportunities for therapeutic intervention in the central nervous system. This PLOS ONE Collection highlights research into the structure, function, development, and modeling of the blood-brain barrier in health and pathology, as well as novel approaches to interact with the central nervous system via the blood-brain barrier.

Biodiversity Conservation

Biodiversity is the backbone of ecosystems and maintaining diversity through conservation is critical for the stability of all ecosystems. The need has never been greater for research that addresses key processes that threaten biodiversity and explores solutions necessary for meaningful conservation. From the impacts of deforestation in the Amazon to pathways of introduction of invasive plants, and from potential effects of global warming on species distributions to the latest advances in conservation genetics for endangered species, this Collection brings together state-of-the-art research in biodiversity conservation from diverse fields and perspectives. 

Plastics in the Environment

Plastic pollution in the natural environment is a global problem, with an estimated five trillion plastic pieces weighing over 250,000 tonnes afloat in the oceans in 2014 [1]. Plastic pollution has the potential to significantly negatively impact the earth system and biosphere in the long-term. With global plastic production increasing, society is at a crucial point for tackling the challenge of ongoing plastic pollution, through a better understanding of the extent and distribution of the problem, the range of impacts of plastic on the environment and ecosystems, ways to reduce the generation of plastic waste and litter, and mitigating the effects of plastic already present in the environment. 

Neuroscience of Reward and Decision Making

Humans and other animals must make decisions in order to survive. To make a decision, it is necessary to consider the costs and benefits of a given choice and learn from the resulting outcomes to make better decisions in the future. Abnormal reward and decision making processes are core components of many psychiatric disorders and are believed, in part, to contribute to the psychosocial problems observed in individuals with these disorders. PLOS ONE, PLOS Biology, and PLOS Computational Biology are proud to present this Collection, which provides insights into the neural basis of reward and decision making, with included papers using techniques such as functional magnetic resonance imaging, electroencephalography, and optogenetic stimulation.

Photovoltaic Solar Cell Materials — Design, Fabrication and Testing

PLOS ONE is pleased to announce the launch of a new collection: Photovoltaic Solar Cell Materials – Design, Fabrication and Testing. Photovoltaic solar cells present new opportunities to provide clean energy worldwide, and the search for more cost- and energy-efficient systems has led to an increasingly broad field of research. As such, we have curated a multi-disciplinary collection that aims to represent this diverse field and to provide a platform that links researchers from various specializations, including chemistry, engineering and materials science.”

Microbes and Host Cell Membrane Interactions

From binding and altering signaling cascades at the cell surface, to membrane penetration and hijacking of intracellular host membranes, microbes and their toxins interact with host cell membranes in seemingly endless ways with sometimes devastating results for the host. In this PLOS collection featuring research from PLOS Pathogens and PLOS ONE we highlight the variety of processes used by different bacteria and viruses to interact with and use their hosts' membranes. 

Stem Cell Plasticity in Tissue Repair and Regeneration

Stem cells bring hope to revolutionize biomedical fields given their potential to give rise to any cell type in the body. The papers included in this collection reflect the interdisciplinary nature of current stem cell research, covering basic, translational and clinical studies. The research highlighted here also shows how the dynamic functions of stem cells can be harnessed to regenerate damaged or lost tissues, which is particularly important for diseases where no established treatments exist.

Life in Extreme Environments

PLOS ONE and PLOS Biology are delighted to publish a Collection on the topic of Life in Extreme Environments, bringing together studies from different disciplines such as biosciences, geosciences, planetary sciences, oceanography and related disciplines in order to shed light on this crucial topic, and to present this research to the broad readership of PLOS ONE and PLOS Biology.

Early Diagnosis and Treatment of Alzheimer's Disease

PLOS ONE is excited to publish a Collection on the early diagnosis and treatment of Alzheimer's disease. As the aging population continues to grow, the prevalence of Alzheimer’s disease is expected to rise. The disease incurs enormous economic and social costs and represents a major public health burden. This Collection includes work that provides insights into potential avenues for the treatment of the disease. This is complemented by a wealth of studies which report on potential markers of Alzheimer's, including how adoption of machine learning techniques can assist in its detection. Through a combination of advances in the treatment and diagnosis of Alzheimer's disease this Collection takes us closer to reducing the global burden of the disorder.

Mathematical Modelling of Infectious Disease Dynamics

Mathematical modelling of biological processes has contributed to improving our understanding of real-world phenomena and predicting dynamics about how life operates. Mathematical approaches have significantly shaped research on disease and evolving epidemics across the globe by providing real-time decision support. Modelling can help describe and predict how diseases develop and spread, both on local and global scales. In addition, mathematical modelling has played a critical role in understanding and measuring the impact of intervention strategies such as vaccination, isolation, and treatment.

The Microbiome Across Biological Systems

Microbiomes are complex communities of bacteria, fungi, archaea, viruses, and microscopic eukaryotic organisms that can inhabit diverse environments, from the human gut, to soil, to even the atmosphere. These communities can impact an equally wide range of processes, including human brain development, pathogen virulence, and ecosystem nutrient cycling. New technologies and methods for studying microbiomes—their composition, formation, and how they influence their surroundings—are constantly emerging and researchers are only just starting to untangle these complex interactions. PLOS ONE and PLOS Biology are excited to publish a shared Collection on the topic of microbiomes across biological systems.

Science of Stories

Stories have the power to shape our identities and worldviews. They can be factual or fictional, text-based or visual and can take many forms—from novels and non-fiction to conspiracy theories, rumors and disinformation. This Collection includes primary research papers that propose innovative, data-driven approaches to understanding stories and their impact, on such topics as the nature of narrative and narrative thinking, methods to extract stories from datasets and datasets from stories, the role of narrative in science communication, and the transformative power of stories.

Future Crops

From the utilisation of neglected crop species and wild relatives to the engineering of enhanced pest resistance, and from analysis of weed competition to improved modelling approaches for plant breeding, this Collection brings together timely research into the many routes to improved crop production. The diverse selection of articles highlights important developments across the breadth of crop science.

Antimicrobial Resistance

An increasingly pressing public health issue, antimicrobial resistance currently imposes a high burden on health care systems globally and is projected to have a significant and worsening impact in the coming decades. To highlight current research, PLOS Biology, PLOS Medicine, and PLOS ONE have launched a Call for Papers focusing on antimicrobial resistance in all microorganisms.

Autophagy and Proteostasis

The importance of proteostasis is becoming increasingly apparent as disrupted proteostasis and dysregulation of the proteostasis network and autophagy is associated with aging and many age-associated diseases. The papers in this Collection provide insight into the molecular and cellular machinery and mechanisms that regulate autophagy and other proteostasis pathways.

Urban Ecosystems

Urban ecosystems occur at the nexus between urbanisation, microclimate, natural resources, organisms and human societies, and PLOS ONE recognises the significance of research that makes connections across these dynamic and complex systems. From the effects of urbanisation on the ecology of urban biota to the social benefits of urban biodiversity, and from the influence of the built environment on global climate change to innovation in microclimatic monitoring, this call for papers aims to bring together diverse perspectives on the physical, biological and social functioning of urban ecosystems.

Targeted Anticancer Therapies and Precision Medicine in Cancer

While the rate of death from cancer has been declining since the 1990s, an estimated 9.6 million people died from cancer in 2018, making it the second-leading cause of death worldwide. There is clearly still an unmet need to improve cancer detection and bring new treatment options to patients. These articles in this Collection represent diverse facets of ongoing efforts in this area, where general knowledge of cancers serves to inform individual patient’s care, and - at the same time - particulars from individual cancer cases contribute to improved resolution of our general knowledge pool.

Substance Use, Misuse, and Dependence: Prevention and Treatment

Substance use and misuse affect people worldwide, of all ages and from all walks of life, resulting in a substantial burden of ill health and mortality, and presenting big challenges in prevention and treatment. Our goal for this Collection is to bring together clinicians and researchers from all the specialties involved in caring for people and communities impacted by substance use disorder, to stimulate research and strengthen the knowledge and expertise to combat the consequences of substance use and misuse.

Maternal and Child Health & Nutrition

In many parts of the world maternal and child health outcomes are increasingly impacted by indirect causes, many of which are related to nutrition. Women with diabetes, anemia or who are overweight are at a higher risk of childbirth-related complications. Their newborns, in turn, are also at a higher risk of experiencing adverse health outcomes later in life. With nearly one in three persons suffering from at least one form of malnutrition in the world – from undernutrition to obesity via diet-related non-communicable diseases – and infant nutrition being crucial particularly in the first 1,000 days of life, this PLOS Medicine and PLOS ONE Collection highlights the importance of nutrition for maternal and child health.

New Tools and Strategies for Tuberculosis Diagnosis, Care, and Elimination

As the leading infectious cause of death worldwide, TB demands an urgent response that will realistically enable its elimination. Despite increases in funding for TB prevention and care in recent years, progress still lags behind targets for the WHO’s End TB Strategy. This PLOS Medicine special issue focuses on new approaches to fighting and ending TB, including discovery and validation of novel biomarkers and diagnostic technologies, development of new treatments, testing of vaccines, and implementation studies of new strategies for diagnosis and treatment of TB.

Machine Learning in Health and Biomedicine

Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate promise, but head-to-head comparisons to classical analyses of clinical data indicate that restraint is warranted. In this Collection, PLOS ONE, PLOS Computational Biology, and PLOS Medicine feature research that applies machine learning methods to health and biomedicine. These articles will be accompanied by expert commentary on the application, impact, and ethics of these approaches.

Open Biomaterials Research

From drug delivery to artificial organs, the design, development, and characterization of biomaterials opens countless avenues for improved medical therapeutics and diagnostics. As the importance of biomaterials research for healthcare grows, so does the need for the corresponding results to be open, well-reported and reproducible. In this PLOS ONE collection, we bring together the biomedical and materials science research communities, to foster interdisciplinary exchange on a wide range of topics and on questions of reporting standards and openness in the field of biomaterials.

Open Quantum Computation and Simulation

Quantum computation and simulation have seen enormous progress in the past few years. Leaps in number and quality of experimentally available qubits, innovations in quantum software and an increasing versatility in simulating quantum matter and quantum systems, nourish the expectation that soon quantum computers and simulators will be able to solve practically relevant problems. In this collection PLOS ONE hopes to encourage greater transparency and reproducibility in research through open availability of source code.