Research Analysis & Science Policy

Editor's Picks: Understanding the Gender Imbalance in STEM Fields

The articles in this collection consider factors associated with the inclusion and success of women in STEM fields and propose ways to reduce the gender gap.

Open Data

This collection highlights the broad scope of research, guidelines, and commentaries about data sharing, data practices, and data policies.

PLOS Biology: Research Matters

Leading scientists explain why the research carried out in their laboratories - and those of their collaborators and their colleagues - matters.

PLOS Biology: Meta-Research

Featuring articles that aim to improve the standards, reproducibility, and evaluation of scientific research.

PLOS Pathogens: Research Matters

PLOS Pathogens presents Research Matters as a means to bridge the gap between academic research and the public. Research Matters provides a forum for active scientists to tell the public how diverse fundamental research into pathogens assures real and compelling impact on public health, human knowledge, and life as well as to develop a collective voice of the pathogens research community.

The Missing Pieces: A Collection of Negative, Null and Inconclusive Results

The publication of negative, null and inconclusive results is important to provide scientists with balanced information and avoid the duplication of efforts testing similar hypotheses, which waste valuable time and research resources in the process.

PLOS Computational Biology: Topic Pages

The Topic Pages collection aims to increase the coverage of computational biology topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.

Public Engagement in Science

This series aims to investigate whether, and under what conditions, it is possible to engage the public in scientific issues in meaningful ways in decision-making about the innovation pathways of biosciences.


Altmetrics is the study and use of non-traditional impact measures that are based on activity in web-based environments. As scholarship increasingly moves online, these metrics track associated interactions and activity to allow researchers and policy makers to understand the reach and impact of research.

Reporting Guidelines

Highlighting articles including guidance, commentary, and related research on repoarting guidelines. This collection features some of the many resources available to facilitate the rigorous reporting of scientific studies, and to improve the presentation and evaluation of published studies.

Ten Simple Rules

"Ten Simple Rules" provide a quick, concentrated guide for mastering some of the professional challenges research scientists face in their careers. 

Open Access

In keeping with our primary mission of making the world’s scientific and medical literature a public resource, PLOS periodically publishes articles that explore the issues surrounding open access. Selected articles are featured to highlight key issues relating to open access.


Ghostwriting misrepresents authorship credit and accountability and is therefore considered unethical, dishonest, and a threat to the integrity of the medical literature.This collection gathers together research and commentary from PLOS journals on the topic of ghostwriting.

Animals, Research, and Alternatives: Measuring Progress 50 Years Later

This Collection touches on the myriad of ethical and scientific issues surrounding the use of animals in research with the aim of spurring ethical and scientific advancement.

The Geopolitics of Neglected Tropical Diseases

To commemorate the Fifth Anniversary of the launch of PLOS Neglected Tropical Diseases, this collection focuses on geographic perspectives on the global burden of the neglected tropical diseases. 

Translational Bioinformatics

'Translational Bioinformatics' is a collection of PLOS Computational Biology Education articles which reads as a "book" to be used as a reference or tutorial for a graduate level introductory course on the science of translational bioinformatics.

The Changing Nature of Global Health Institutions

A four-part series from PLOS Medicine examining the ways in which global health institutions and arrangements are changing and evolving.

Disease Mongering

To mark the first academic meeting on disease mongering (the "selling of sickness" in order to promote drug sales), which was held in Newcastle, Australia in April 2006, and to help provoke and inform a response to the phenomenon, PLOS Medicine commissioned a special theme issue

Evaluating eHealth Collection

A three part series examining the emergence of eHealth – the use of electronic tools in delivering health care – and its benefits and challenges worldwide.

PLOS Neglected Tropical Diseases: Historical Profiles and Perspectives

To commemorate the Fifth Anniversary of the launch PLOS Neglected Tropical Diseases a number of "Historical Profiles and Perspectives" articles were published, highlighting individual researchers or institutions that have contributed significantly to progress within the field.

Are Drug Companies Living Up to Their Human Rights Responsibilities?

The PLOS Medicine Debate asks whether drug companies are living up to their human rights responsibilities.

Core Facilities

These articles aim to explain how to set up and administrate Core Facilities, and the benefits to researchers and institutions of so doing.

TDR Reflects on 40 Years

Former and current staff of the Special Programme in Research and Training in Tropical Disease (TDR) provide their views on key challenges and lessons learned during the 40 year history.


The number and scope of scientific databases has soared in recent years, creating a new profession, the biocurator. These "museum catalogers of the Internet age" face a continuous struggle of making ever growing amounts of data accessible.

PLOS Computational Biology: Editors' Outlook

The PLOS Computational Biology Editors' Outlook collection provides diverse mini reviews from members of the Editorial Board on their research areas, and includes discussions of new and future developments.

The Roots of Bioinformatics

This collection of essays from prominent workers in the field of bioinformatics relates how selected scientific, technological, economic, and even cultural threads came to influence the development of the field we know today.

Bioinformatics: Starting Early

Bioinformatics is being introduced into the school curriculum earlier and earlier as the field matures. “Bioinformatics: Starting Early” is devoted to teaching bioinformatics in secondary schools.

About My Lab

'About My Lab' was launched with the mission to share knowledge about lab organization and scientific management. Each Perspective represents an interview with a Principal Investigator, who shares his or her experience of running a lab by discussing selected topics in an informal and personal style.

Developing Computational Biology

A series of Perspective articles from computational biologists in a variety of countries, each of whom offers their personal viewpoint on the history, current status, and future of computational biology in their region.

Stories from the Road: ISCB Student Council Collection

For the past 10 years the International Society for Computational Biology (ISCB) Student Council has provided events and activities to help support and encourage young budding scientists. This article series, written by past and present student council members, shares some of the trials and tribulations of the ISCB student community.


Recognizing the need for training and education in bioinformatics and computational biology specifically targeted to biologists, PLOS Computational Biology launched its Education section in January 2006. The goals are to provide practical tutorials and background information on important computational methods.