The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Starworms
The Starworms (STop Anthelminthic Resistant WORMS) project aims to strengthen the monitoring and surveillance of drug efficacy and anthelmintic resistance in soil-transmitted helminth control…
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Medicine & Health Trafficking, Exploitation and Health
The health consequences of human trafficking and exploitation are sufficiently prevalent and damaging that they comprise a public health problem of global magnitude. This PLOS Collection offers…
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Research Analysis & Policy The Missing Pieces: A Collection of Negative, Null and Inconclusive Results
The publication of negative, null and inconclusive results is important to provide scientists with balanced information and avoid the duplication of efforts testing similar hypotheses, which waste…
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Medicine & Health Regulatory Harmonization Collection
While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…
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Medicine & Health The BIRTH Special Collection
In 2014, the EU funded a COST Action that brought together over 120 scientists, practitioners, activists and policy makers from 34 countries, to advance research and practice in an area of great…
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Medicine & Health Advances in Clinical Trial Design for Development of New Treatments for Tuberculosis
With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…
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Medicine & Health Economic Efficiency of HIV Services
In order to maximize the value for money for HIV services and increase efficiency without sacrificing quality, robust and up-to-date data on costs, efficiency and its determinants are needed…
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Medicine & Health Economic Cases for NCD Prevention and Control: A Global Perspective
Economic Cases for NCD Prevention and Control expands the evidence base on the economic burden of noncommunicable diseases (NCDs) and the impact of NCD prevention and control programs globally. This…
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Medicine & Health DeWorm3
Soil-transmitted helminths infect an estimated 1.45 billion people globally. The current WHO strategy for controlling STH is based on controlling morbidity via mass drug administration of medications…
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Medicine & Health High-Quality Health Systems
High quality health care will be critical to attaining the Sustainable Development Goals in low- and middle income countries. However, little is known on levels of quality and its distribution within…