The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Dementia: Across the Lifespan & Around the GlobeView Collection
Alzheimer’s Disease International (ADI) estimates there will be over 131.5 million people living with dementia by 2050, as well as a shift in burden from the richest to poorest…
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Biology & Life Sciences Editor’s Picks: Cell BiologyView Collection
Cell biologists investigate fundamental aspects of life, from the basic building blocks of the cell to how cells grow, divide and interact with each other. In conjunction with the 2018 ASCB Meeting…
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Medicine & Health Traumatic InjuryView Collection
Traumatic injury has long been recognized as a neglected disease of extremely high burden. With this Special Issue, PLOS Medicine and guest editors Professor Karim Brohi and Dr Martin Schreiber…
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Computer & Information Sciences PLOS Computational Biology Benchmarking CollectionView Collection
Research in computational biology has given rise to a vast number of methods developed to solve scientific problems. For areas in which many approaches exist, researchers have a hard time deciding…
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Medicine & Health Editor’s Picks: Co-Infection in Tropical MedicineView Collection
Co-infection with more than one pathogen is a continuing challenge in global health, particularly in regions with multiple endemic infectious diseases. Direct and indirect interactions between…
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Research Analysis & Policy Meta-Research: Sources of BiasView Collection
Meta-research, or the scientific study of research practices, aims to characterize existing standards and ultimately improve the quality and reliability of scientific research. We collect here…
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Earth & Environment Confronting Climate Change in the Age of DenialView Collection
Most scientists believe that climate change is one of the greatest challenges of our time -- if not the greatest challenge. Yet too often, efforts to communicate science-based information about the…
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Research Analysis & Policy Editor’s Picks: Understanding the Gender Imbalance in STEM FieldsView Collection
Increasing numbers of women are entering science, technology, engineering, and mathematics (STEM) disciplines at undergraduate and graduate levels. However, women remain underrepresented at higher…
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Earth & Environment Open Highlights: Birds, Blooms, and Evolving DiversityView Collection
How the traits that distinguish species develop and diversify over time is a long-standing question in the field of evolutionary biology. This Open Highlight investigates how species have evolved…
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Research Analysis & Policy Publishing Dual Use Research of Concern: A Case StudyView Collection
The implications of publishing dual use research of concern (DURC) continues to be a topic widely and deeply discussed in the scientific community. In a series of Opinion articles, PLOS Pathogens…