While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…

The work of Denise Barlow revolutionised the field of epigenetics. She spent the majority of her career identifying and studying the mechanistic regulation of the Igf2r imprinted gene cluster and as a…

In 2014, the EU funded a COST Action that brought together over 120 scientists, practitioners, activists and policy makers from 34 countries, to advance research and practice in an area of great…

At PLOS Pathogens we publish outstanding research on pathogenic organisms including bacteria, fungi, parasites, prions and viruses. Each year, we celebrate the impact our authors have had and share…

Stories have the power to shape our identities and worldviews. They can be factual or fictional, text-based or visual and can take many forms—from novels and non-fiction to conspiracy theories…

With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…

Stem cells bring hope to revolutionize biomedical fields given their potential to give rise to any cell type in the body. The papers included in this collection reflect the interdisciplinary nature of…

PLOS ONE is excited to publish a Collection on the early diagnosis and treatment of Alzheimer's disease. As the aging population continues to grow, the prevalence of Alzheimer’s disease is…

The strict regulation of the microenvironment by the blood-brain barrier is a key component of central nervous system function. Changes in the structure and function of this unique and dynamic…

The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…