This collection builds on the previous priority setting process to publish key evidence reviews with complimentary targeted commentaries that inform the updated 2021 guidelines. Supporting evidence…

Cells use elaborate mechanisms to sense a variety of mechanical and biochemical cues in their environment, to integrate this information, and to generate coherent adaptive responses. A more complete…

Mental health disorders are common and effective treatments are often available, however affected individuals often struggle to access care. Mobile health (mHealth) resources are increasingly…

Global food demand places significant pressure on the environment and human societies, including land degradation, deforestation, water scarcity and food inequality. Sustainable agriculture is crucial…

The efficacy and safety of a drug is highly impacted not only by how it is designed, but also by how and where it is delivered. In recent years there has been significant progress in the formulation…

This Collection highlights some of PLOS Biology’s Meta-Research articles since 2016 as well as some of PLOS ONE’s articles over the past few years, all about “research on research,” or the…

Transparency in reporting and methodological rigor have received increasing interest in psychology and cognitive science. They are crucial ingredients in ensuring the replicability of our findings…

PLOS ONE is committed to pushing the boundaries of Open Science by improving the reproducibility and transparency of scientific research. Earlier this year we launched Lab Protocols in collaboration…

Issues on health care access have recently been put in sharp relief, as the current COVID-19 pandemic highlights the importance of strengthening health infrastructure and workforce around the world…

Domestication of wild animal and plant species may be considered the largest genetic experiment in human history. Human selection for specific traits and targeted breeding over hundreds or thousands…