The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Regulatory Harmonization Collection
While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…
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Biology & Life Sciences Genomic Imprinting and Epigenetic Regulation: A Tribute to Denise Barlow
The work of Denise Barlow revolutionised the field of epigenetics. She spent the majority of her career identifying and studying the mechanistic regulation of the Igf2r imprinted gene cluster and as a…
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Medicine & Health The BIRTH Special Collection
In 2014, the EU funded a COST Action that brought together over 120 scientists, practitioners, activists and policy makers from 34 countries, to advance research and practice in an area of great…
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Biology & Life Sciences PLOS Pathogens Top 10%
At PLOS Pathogens we publish outstanding research on pathogenic organisms including bacteria, fungi, parasites, prions and viruses. Each year, we celebrate the impact our authors have had and share…
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Computer & Information Sciences Science of Stories
Stories have the power to shape our identities and worldviews. They can be factual or fictional, text-based or visual and can take many forms—from novels and non-fiction to conspiracy theories…
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Medicine & Health Advances in Clinical Trial Design for Development of New Treatments for Tuberculosis
With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…
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Biology & Life Sciences Stem Cell Plasticity in Tissue Repair and Regeneration
Stem cells bring hope to revolutionize biomedical fields given their potential to give rise to any cell type in the body. The papers included in this collection reflect the interdisciplinary nature of…
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Medicine & Health Early Diagnosis and Treatment of Alzheimer’s Disease
PLOS ONE is excited to publish a Collection on the early diagnosis and treatment of Alzheimer's disease. As the aging population continues to grow, the prevalence of Alzheimer’s disease is…
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Biology & Life Sciences Blood-Brain Barrier Biology in Health and Pathology
The strict regulation of the microenvironment by the blood-brain barrier is a key component of central nervous system function. Changes in the structure and function of this unique and dynamic…
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Biology & Life Sciences ’Omics of Cellular Signaling Pathways
The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…