Biology & Life Sciences


Calls for Papers for PLOS Collections

Antimicrobial Resistance 

PLOS ONE, PLOS Biology, PLOS Medicine

& PLOS Neglected Tropical Diseases

Autophagy and Proteostasis

PLOS Biology and PLOS ONE


PLOS ONE, PLOS Biology & PLOS Pathogens


PLOS Special Collections

Read more about PLOS Special Collections on the Special Collections information page

Craniofacial Genetics

This collection contains a curated selection of research with a focus on specific areas of interest: craniofacial morphogenesis, dysmorphology and syndromes, and normal human facial variation.

PLOS Genetics Research Prize

Each year, you are invited to nominate your favorite PLOS Genetics Research Article for our Research Prize, an initiative that recognizes and rewards outstanding primary research.

GLBIO 2017

A collection of research papers from the 12th Great Lakes Bioinformatics Conference (GLBIO) 2017, organized by the GLBIO Consortium.

Focus Features: Network Approaches and Applications in Biology

This Focus Feature, led by Ruth Nussinov and Trey Ideker, addresses some of the most exciting current opportunities and challenges in the field of Network Biology.

Up For A Challenge (U4C) – Stimulating Innovation in Breast Cancer Genetic Epidemiology

The four winning articles from the National Cancer Institute’s competition appear in this special collection, published by PLOS Genetics.


PLOS NTDs has long been a home for vector research. With this collection, we aim to curate the cutting edge of vector research from the global NTDs community.

Chemical Tools & Probes

PLOS ONE Associate Editor Carla Pegoraro highlights some of the latest research on the development and uses of chemical probes, including in vivo and in vitro imaging, drug discovery, protein functions and cellular processes.

Editor’s Picks: Autophagy

PLOS ONE Associate Editor Adya Misra showcases some of the research highlighting the importance of autophagy in cancer and neurodegenerative disease as well various modulators of this process.

PLOS Neglected Tropical Diseases: 10th Anniversary Collection

The articles in this collection reflect on significant lessons and successes in the field over the past decade since the journal launched.

Yellow Fever

PLOS NTDs Editor-in-Chief Serap Aksoy has assembled a collection of previously-published Yellow Fever research articles that are of interest considering the 2015-2016 outbreaks of Yellow Fever in Africa and Brazil.

PLOS iGEM 2016

PLOS hosted a realtime online peer review event for iGEM teams ahead of submission to the PLOS iGEM 2016 Collection.


Leishmaniasis research papers from the call for papers made by the WorldLeish-6 Scientific Committee, in partnership with PLOS Collections.

Bridging Communities: Co- and Polymicrobial Infections

PLOS Pathogens presents Research Articles that directly tackle how overlapping infections, and the immune responses they stimulate, might interact in novel ways.

Editor’​s Picks: Molecular Biology & Biochemistry

This collection, as selected by PLOS ONE Associate Editor, Adya Misra, highlights publications that represent recent developments in molecular biology with a special focus on genome editing and high throughput sequencing.


The impact of zika, an arbovirus infection transmitted by several different species of Aedes mosquitoes, should be treated with the utmost seriousness as the impact could be devastating.

Editor’s Picks: Cell Biology

Research exploring how cells work helps us understand the proper functioning of the body, as well as understand and treat disease. Senior Editor Meghan Byrne has selects recent papers highlighting the critical research PLOS journals publish in this area.

Editor’s Picks: Human Genetics

PLOS ONE Senior Editor, Eric Martens shares a sampling of exciting Human Genetics research from PLOS journals.

Open Highlights

Open Highlights use recent PLOS Biology research articles as keystones around which to nucleate a short synthesis of up to ten related research articles from other PLOS journals and from the wider Open Access corpus.

Editor’​s Picks: Uncovering Evolutionary Patterns in the Tree of Life

In this Editor’s Picks, PLOS ONE Associate Editor Sara Fuentes Perez selects recent PLOS publications highlighting the wide implications of evolutionary biology including environmental adaptation, conservation and host-parasite interactions.

Epidemiological Investigations of North American Zoo Elephant Welfare

This collection investigates a series of questions about the welfare of North American zoo elephants using epidemiological methods. The studies provide objective information about how the elephants are faring, identify the most salient connections between their daily lives and a range of behavioral and physical welfare outcomes, and support advances in evidence-based zoological management.

Editor’s Picks: Stem Cell Research

PLOS Staff Editors Eric Martens, Ines Alvarez-Garcia and Jenna Wilson share recent PLOS articles highlighting the many facets of stem cell research.

The Global Burden of Norovirus & Prospects for Vaccine Development

Each year, norovirus causes over 200,000 deaths and a global economic burden of more than $60 billion.  In this PLOS Collection global norovirus experts fill critical knowledge gaps and provide key information to further development of a much-needed vaccine.

PLOS iGEM 2015

PLOS and iGEM share a belief that science is best advanced through openness. Submissions to the PLOS iGEM Collection will be posted for open review on the PLOS Collections blog, where members of the PLOS and iGEM communities will review them openly.

Cancer Research

New research is being regularly published on preventing and curing cancer. This Collection highlights cancer research published in PLOS journals.

Understanding Images

Understanding Images is a collection of posts and articles from a PLOS Genetics blog series. The aim of the series is to showcase the research that created or inspired the journal's cover image, and explain how the image helps us to understand the research question addressed in the manuscript.

Editor’s Picks: Microbiology

PLOS ONE Senior Editor, Meg Byrne selects recent PLOS articles highlighting the varied research ongoing into understanding the complexities of microbiology.

Editor’s Picks: Single Cell Genomics

In this Editor’s Picks, PLOS ONE Associate Editor Nicola Stead selects recent PLOS publications highlighting recent advances in single-cell technologies and the biological insight provided by single cell genomics.

Editor’s Picks: Experimental Biology

Associate Editor, Renee Hoch selects articles that aim to advance our knowledge of physiology, development, & disease.

Slice of PLOS

Slice of PLOS highlights papers from across the PLOS journals, from mesocosms and climate change to the awesomeness of bats.

Deep Reads

"Deep Reads" celebrates science in literature with the aim of providing recommendations for books in the realms of genetics and beyond

PLOS Pathogens: 10th Anniversary Collection

To celebrate the 10th anniversary of the launch of PLOS Pathogens, over 60 Section Editors, all experts on studies of viruses, bacteria, prions, fungi, oomycetes and parasites of animals and plants, were invited to select articles that they believed represented the very best exemplars from their respective fields.

PLOS Genetics: 10th Anniversary

2015 marks the tenth anniversary of PLOS Genetics and brings with it a host of celebrations to mark this momentous occasion. This collection exhibits some of the best research PLOS Genetics has had the privilege to publish over the past decade.

PLOS Pathogens Pearls

PLOS Pathogens presents an Open Access compendium of "lessons-that-last." This living collection of short, educational, and highly useful articles addresses topics of relevance and importance within the wide-ranging field of pathogens research, with insights tailored to graduate students and post-docs.

Malaria: Targets and Drugs for All Stages

This Collection describes multiple parasite and host processes engaged in infection in blood, the blocking of which could stop human illness. Control and eradication of malaria will also require the development of drugs against stages responsible for mosquito transmission and those that remain latent in the liver.

Sauropod Gigantism: A Cross-Disciplinary Approach

This new PLOS Collection discusses major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. The articles address these questions from the widest selection of disciplinary viewpoints, including those of ecology, engineering, functional morphology, animal nutrition and palaeontology.

Synthetic Biology Collection

Broad categories focus on DNA synthesis and assembly techniques, the development of libraries for biological parts, the use of synthetic biology in protein engineering applications, work focussing on synthetic life and multicellular systems, gene editing, and the engineering of gene regulatory networks and metabolic pathways.

Neuroscience Collection

This collection represents a first step in gathering under easily identifiable rubrics some of the most recent neuroscience research published across the PLOS journals. The Collection has been organized into broad categories to provide more structured and efficient access to papers of interest in the PLOS corpus.

Clinical Immunology Collection

The Clinical Immunology Collection includes sections on Allergies & Anaphylaxis, Tumor Immunology, Immunodeficiency and Autoimmune Diseases.

Advances in HIV Mucosal Immunology: Challenges and Opportunities

This collection reports the results of the efforts of investigators, in providing important, practical details on studying immune responses in the genital and rectal mucosa, which will help guide future studies of HIV prevention.


This collection collates some of the best and most recent immunobiology articles published at PLOS, featuring papers that examine cellular and molecular immunology, evolutionary immunology, animal models of the human immune system and ontogeny of the immune system.

The Promise of Plant Translational Research

The technical advances highlighted in this collection exemplify how basic research discoveries are being translated into methods to develop and improve, both agriculturally and environmentally, important crop traits.

Public Engagement in Science

This series aims to investigate whether, and under what conditions, it is possible to engage the public in scientific issues in meaningful ways in decision-making about the innovation pathways of biosciences.

Ecological Impacts of Climate Change

The ecological impacts of climate change are broad and diverse, altering species' range limits, plant phenology and growth, carbon and nutrient cycling, as well as biodiversity and extinction risk.

Marine Megafauna Collection

The Marine Megafauna Collection presents research focused on the biology, ecology and conservation of the most captivating creatures in the ocean. 

Tsetse Genome Biology Collection

This collection contains manuscripts that describe functional findings on various tsetse biology. In addition two manuscripts reflect on the unique historical aspects of sleeping sickness epidemics that have plagued sub-Sahara in the 20th century.

Visceral Leishmaniasis and HIV Co-Infection

PLOS Neglected Tropical Diseases has dedicated a special collection to VL-HIV co-infection including basic and molecular work, immunological and diagnostic studies, clinical studies, and public health aspects.


In response to the 2014 Ebola outbreak in West Africa, PLOS editors curated content from across the seven journals, PLOS Currents and the PLOS Blogs Network into a rapidly evolving collection of research.

Neuromapping and Therapeutics

The NeuroMapping and Therapeutics Collection contains a selection of articles published in PLOS ONE that are representative of the aims and scope of Society of Brain Mapping and Therapeutics.

POST Collection

The Pacific Ocean Shelf Tracking (POST) Program seeks to advance understanding of the movement and behavior of marine animals through the use of a large-scale acoustic telemetry and data management system.

RosettaCon 2014

This special collection describes the results presented at the 2014 RosettaCon conference by participating RosettaCommons labs.

RosettaCon 2012

The Rosetta framework for macromolecular modeling, prediction and design is a widely used code with a large, dynamic developer community.  This special collection presents recent developments from the Rosetta community, drawn from the groups participating in RosettaCon 2012.

RosettaCon 2010

The Rosetta framework for macromolecular modeling, prediction and design is a widely used code with a large, dynamic developer community.  This special collection presents recent developments from the Rosetta community, drawn from the groups participating in RosettaCon 2010.

The Paleontology Collection

This collection represents those articles published in PLOS ONE on the general topic of paleontology (the study of fossils and of life forms that existed in past geological periods).

The Mice Drawer System Experiment and the Space Endurance Record-Breaking Mice

The Italian Space Agency contracted Thales Alenia Space Italia to build a spaceflight payload (Mice Drawer System (MDS)) for mice research on the International Space Station (ISS), including wild type and transgenic strains. These studies examined changes that occurred in the animals.

Stress-Induced Depression and Comorbidities: From Bench to Bedside

This collection of articles represents the output of a group of international research institutions (informally referred to as EUMOOD) who collaborated around the causal link between stress exposure and depression vulnerability.

Prokaryotic Genome Collection

The Prokaryotic Genome Collection is an attempt to present and highlight a number of important articles that describe whole genome sequence and/or comparative genomics of important prokaryotic organisms.

Structural Biology and Human Health: Medically Relevant Proteins from the SGC

This collection of articles represents some of the research highlights from the SGC, an international public-private partnership that determines three dimensional structures of medically important proteins from both human and human parasites and places this information into the public domain, free from restrictions on use. 

RECOMB Regulatory Genomics and Systems Biology 2009

In a joint venture between PLOS Computational Biology, PLOS ONE and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB Satellite onSystems Biology, held jointly at MIT, December 2-6, 2009.

The Human Microbiome Project Collection

Funded by the National Institutes of Health Common Fund, the Human Microbiome Project (HMP) was established to provide a comprehensive baseline of the microbial diversity at 18 different human body sites. The Human Microbiome Project Collection encompasses publications from the project.

Biodiversity of Saba Bank

This collection of articles represents an international collaboration to characterize the richness, diversity, and habitat affinities of marine taxa on Saba Bank. 

A Collection of Interviews by Jane Gitschier

Jane Gitschier brings her unique conversational style to this collection of interviews of interesting people in the world of science and genetics.

The DREAM systems biology challenges: a Dialogue for Reverse Engineering Assessment and Methods

This Collection contains papers representing the output of the best performing methods in the DREAM challenges, which themselves were discussed and presented at the DREAM (Dialogue for Reverse Engineering Assessment and Methods) conferences, which have been running annually since 2007.

Genetically Modified Insect

These articles describe the technical and applied aspects of GM insects. We have also included articles that are not strictly GM, but aim to modify the disease transmission traits of insects through the use of symbiotic microbes.

PLOS Neglected Tropical Diseases: Top Ten Research Article Collection

To commemorate the Fifth Anniversary of the launch of PLOS NTDs, we are releasing a collection of the most-viewed research articles from each of the five years that the journal has published.

Aging: Bench to Bedside

This collection focuses on a rapidly evolving field in which the study of both species-specific and ubiquitous aging mechanisms informs the biological process of aging.

2009 Maize Genome

The authors of the research presented in this special collection used the first description of the B73 maize genome to probe some of the most intriguing questions in genetics and plant biology.

Tenth Anniversary PLOS Biology Collection

In celebration of the Tenth Anniversary of PLOS Biology, this collection showcases ten specially selected PLOS Biology research articles, drawn from a decade of publishing excellent science. The articles, which were chosen by PLOS Biology's Editors and Editorial Board, are representative of the high quality research published in the journal over the last decade. 

The Genome Network Project/FANTOM3

This collection features articles describing findings that redefine the landscape of the mammalian transcriptome by introducing an extensive collection of novel cDNAs and millions of sequenced tags corresponding to 5'- and 3'-ends of mRNAs.

Epigenetics 2010

This collection reflects a range of model systems and organisms, and offer phenotypic, mechanistic, and chromatin-based insights.

Oceanic Metagenomics

The J. Craig Venter Institute's Global Ocean Sampling Expedition revealed an enormous amount of unexplored diversity in the world's oceans. This collection includes commentary and analysis highlighting the achievements and challenges of this work.

Genomics of Emerging Infectious Disease

This collection of essays, perspectives, and reviews from six PLOS Journals provides insights into how genomics can revolutionize our understanding of emerging infectious disease.

The World Register of Marine Species

This Collection has been created by the editors of the World Register of Marine Species, an open-access online database which holds information on all marine species, and some of their freshwater and terrestrial relatives.

Diversity in the Nearshore: The NaGISA Collection

This collection of papers highlights research performed under the auspices of the Natural Geography in Shore Areas (NaGISA) project, a component of the Census of Marine Life Project.

Marine Life on Seamounts – The CenSeam Collection

This collection is part of the Census of Marine Life Project and brings together the latest seamount papers, enabling a wide variety of scientific results to be linked. 

Biogeography of Deep-Water Chemosynthetic Ecosystems - The ChEss Collection

This Collection presents some of the recent advances in biogeography and taxonomy within deep-sea chemosynthetic environments. 

Marine Biodiversity and Biogeography - Regional Comparisons of Global Issues

Through a global network of researchers in more than 80 nations, the Census of Marine Life (2000-2010) has engaged in a coordinated scientific program to assess and explain the diversity, distribution, and abundance of life in the oceans.

HMAP Collection

The History of Marine Animal Populations is a global research initiative to study the past ocean life and human interaction with the sea.

FMAP Collection

This collection of papers highlights research performed under the auspices of the Future of Marine Animal Populations (FMAP) program, a component of the Census of Marine Life Project.

MarBOL Collection

This collection of papers presents research in the field of Marine Barcoding under the auspices of MarBOL: a joint effort of the Consortium for the Barcode of Life (CBOL) and the Census of Marine Life to enhance our capacity to identify marine life by utilizing DNA barcoding.

The TOPP Collection

This collection of papers highlights research performed under the auspices of the Tagging of Pacific Predators (TOPP) program, a component of the Census of Marine Life (CoML). TOPP is a multi-institutional, multi-year large-scale biologging program that has deployed nearly 4300 tags on 23 marine species throughout the Pacific Ocean.

Challenges Collection

This collection of brief provocative discussion papers, initiated and edited by Simon Levin, aims to highlight fundamental questions in biology that cut across and help unify different biological disciplines.

PLOS Pathogens & PLOS Neglected Tropical Diseases Twinning Collection

PLOS Pathogens and PLOS Neglected Tropical Diseases sent a collection of primary research articles on topics spanning these sister journals, including: proteomics, kinetoplastids, insect vectors, genomics, and transcriptomics within the context of the NTDs.