The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Biology & Life Sciences The many facets of immunometabolismView Collection
This Collection of articles aims to shine a light on the many facets of immunometabolism, highlighting how molecular and cellular mechanisms impact diverse tissue and organismal functions and the…
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Biology & Life Sciences Unveiling cancer crosstalk across spatial and temporal scalesView Collection
This collection focuses on how recent technological advancements in omics approaches (genomics, proteomics, metabolomics etc.) have enhanced our understanding of the mechanisms governing tumor…
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Biology & Life Sciences The promises and challenges of neurotechnology to improve human health and cognitionView Collection
Neurotechnology offers unprecedented opportunities to treat neural disorders, restore brain function and enhance cognitive abilities. However, its vast potential is matched by significant scientific…
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Biology & Life Sciences Bringing data to decision making for conservation and biodiversityView Collection
Translating conservation and biodiversity research from the field into the real world is a complex problem. This collection discusses issues around economics, policy, and how to do research that…
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Biology & Life Sciences PLOS Biology 20th AnniversaryView Collection
As PLOS Biology turns 20 years old, we are celebrating two decades of publishing high-impact life sciences research at the forefront of open science. This collection contains articles that look back…
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Biology & Life Sciences Mendel’s legacy in modern geneticsView Collection
The collection draws on the opinion of experts in the field of genetics, who look back at Mendel’s original research and examine how well it stands up to modern views on genetics, and how it has…
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Biology & Life Sciences Triple drug (IDA) mass drug administration for elimination of lymphatic filariasisView Collection
This collection reports results of clinical trials and community studies of the safety, efficacy, and acceptability of the triple drug regimen IDA (ivermectin plus DEC and Albendazole) as a mass drug…
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Biology & Life Sciences Modeling Cell Proliferation and the Cell MicroenvironmentView Collection
Cells use elaborate mechanisms to sense a variety of mechanical and biochemical cues in their environment, to integrate this information, and to generate coherent adaptive responses. A more complete…
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Biology & Life Sciences Domestic Animal GeneticsView Collection
Domestication of wild animal and plant species may be considered the largest genetic experiment in human history. Human selection for specific traits and targeted breeding over hundreds or thousands…