The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Biology & Life Sciences ImmunobiologyView Collection
Immunobiology is the study of the components that make up the body's immune system, how these arise during embryogenesis and function together, and how they evolve in different organisms in response…
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Biology & Life Sciences Open Highlights: In Search of Autism’s RootsView Collection
This Open Highlights Collection explores recent research investigating the neurodevelopmental origins of autism spectrum disorder and efforts to help those with associated health problems. Open…
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Biology & Life Sciences EbolaView Collection
In response to the 2014 Ebola outbreak in West Africa, PLOS editors curated content from across the journals, PLOS Currents and the PLOS Blogs Network into a rapidly evolving collection of research…
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Biology & Life Sciences Open Highlights: Living Life on a MagnetView Collection
This Open Highlights collection examines recent research into the diverse ways in which living things interact with the Earth’s magnetic field and use it for orientation and navigation…
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Biology & Life Sciences Open Highlights: Wreaking Reproductive Havoc One Chemical at a TimeView Collection
This Open Highlights Collection explores recent research into the adverse effects of environmental synthetic chemicals on development and reproduction…
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Computer & Information Sciences Focus Feature – Genome Landscapes and Phenotype Prediction of DiseaseView Collection
This Focus Feature led by Rachel Karchin and Ruth Nussinov highlights strategies to predict the phenotypic disease consequences of human germline and somatic variation. The rapid growth in genomic…
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Computer & Information Sciences Text MiningView Collection
Across all realms of the sciences, the rapid growth in the number of works published digitally presents new challenges and opportunities for making sense of this wealth of textual information. The…
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Biology & Life Sciences Editor’s Picks: Uncovering Evolutionary Patterns in the Tree of LifeView Collection
Since the conception of the theory of evolution through natural selection by Charles Darwin and Alfred Russel Wallace, evolutionary biology has become central to our understanding of the natural…
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Computer & Information Sciences Focus Feature – Allostery: Concepts, Methods & ApplicationsView Collection
This Focus Feature, led by Jin Liu and Ruth Nussinov, commemorates the 10th anniversary of PLOS Computational Biology and puts a spotlight on Allostery. The research included is a range of both new…
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Computer & Information Sciences Focus Feature – The Ethics of Big DataView Collection
With exciting new research opportunities comes the much needed consideration of ethical challenges. This Focus Feature, led by Philip E. Bourne, addresses the ethical challenges that accompany the use…