The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health malERA – A Research Agenda for Malaria Eradication
The Malaria Eradication Research Agenda (malERA) initiative complements existing research agendas, which are primarily aimed at reducing the global burden of morbidity and mortality due to malaria by…
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Medicine & Health Migration & Health
In May and June 2011, PLOS Medicine published a commissioned six-part series on migration and health. If internal and international migrants comprised a nation, it would be the third most populous…
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Biology & Life Sciences Neurodegenerative Disease Research
The Neurodegenerative Disease Research section of the PLOS Neuroscience Collection includes a selection of research articles published in PLOS journals since 2014. Neurodegenerative diseases are…
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Medicine & Health Social Medicine in the 21st Century
PLOS Medicine's October 2006 issue contained a special collection of eleven magazine articles and five research papers devoted entirely to social medicine. The collection featured many of the leaders…
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Medicine & Health Cancer Immunotherapy
Cancer immunotherapies harness the body’s immune system to fight cancer. In general, immunotherapies either train the immune system to identify and attack cancer cells (e.g. adoptive cell…
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Medicine & Health PLOS Medicine Cancer Research
Knowledge about the causes of cancer and interventions to prevent and manage the disease is extensive and is continually growing. Whilst many patients now have improved prognosis if their cancer is…
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Biology & Life Sciences Zika
Zika is an arbovirus infection transmitted by several different species of Aedes mosquitoes, including Aedes aegypti in the New World. Towards the end of 2015, the Pan American Health Organization…
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Medicine & Health Diabetes Prevention
Diabetes is a global problem, with recent estimates of a staggering 410 million people with diabetes mellitus in 2013. The high risk of disabling and life-threatening complications, and the enormous…
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Biology & Life Sciences Open Highlights: Putting Placebos to the Test
Medics have long recognised the curious power of the placebo. This Open Highlights Collection explores recent research into its biological basis and the complex ethical and practical issues that…
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Biology & Life Sciences The Global Burden of Norovirus & Prospects for Vaccine Development
Each year, norovirus causes over 200,000 deaths and a global economic burden of more than $60 billion. A highly contagious virus that most people will contract 5 times in their lifetime, the most…