The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Ghostwriting Collection
Ghostwriting occurs when someone has made substantial contributions to writing a manuscript but this role is unacknowledged. In medicine, ghostwriting is problematical because it often involves…
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Research Analysis & Policy Open Data
In the spirit of Open Con and highlighting the state of Open Data, PLOS is proud to release our Open Data Collection. In collaboration with our external advisor, Melissa Haendel, we have selected…
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Medicine & Health The Changing Nature of Global Health Institutions
In January 2010 PLOS Medicine launched a four-part series examining the ways in which global health institutions and arrangements are changing and evolving. The series aims to stimulate debate…
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Biology & Life Sciences Epigenetics 2010
Epigenetics is the study of inherited changes in phenotype or gene expression caused by mechanisms other than changes in the underlying DNA sequence. This collection brings together twenty research…
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Biology & Life Sciences Malaria: Targets and Drugs for All Stages
Drug research in malaria often focuses on blood stage parasites because they are responsible for the symptoms of the disease and are easier to manipulate in the laboratory.This collection describes…
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Biology & Life Sciences Genomics of Emerging Infectious Diseases
This collection of essays, perspectives, and reviews from six PLOS journals provides insights into how genomics can revolutionize our understanding of emerging infectious disease. Produced with…
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Medicine & Health Translating the Cancer Genome – Implications for Diagnosis and Treatment
Dramatic reductions in the cost of sequencing, as well advances in sequencing technologies, have enabled key insights into the genomic alterations and somatic mutations that lead to cancer and…
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Biology & Life Sciences Cancer Research
Cancers figure among the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths each year. It is expected that annual cancer…
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Medicine & Health Real-Time Monitoring of Under-Five Mortality
In most low-income countries, Ministries of Health and their partners must rely on periodic household surveys as their primary population-level source of vital statistics. Recent initiatives around…
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Medicine & Health malERA – An updated research agenda for malaria elimination and eradication
‘malERA Refresh’ is a forward-looking research and development agenda that accelerates progress towards malaria elimination and global eradication. The malERA Refresh special collection…